SynthesisAsian Pacific journal of cancer prevention : APJCP2023
The Association between ABO Blood Group and the Risk of Colorectal Cancer: A Systematic Literature Review and Meta-Analysis.
Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies.BMC medicine · 2024Pooled it
- Colitis-Associated Colorectal Cancer-STAT3 Inhibition as a Preventive Strategy.International journal of molecular sciences · 2026Article
- ABO gene polymorphisms: a molecular bridge linking disease susceptibility to therapeutic outcomes.Frontiers in medicine · 2026Review
- ABO blood group and Rhesus factor as potential markers in papillary thyroid cancer: a retrospective comparative analysis (2015-2023).Langenbeck's archives of surgery · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecently, studies have investigated the relationship between blood types and cancers. Contradictory results regarding the relationship between blood group type and colorectal cancer(CC) have been reported. The purpose of this study was to systematically investigate the distribution of ABO blood group frequency and evaluate its relationship with CC. MATERIAL AND
methodsTo conduct this systematic meta-analysis, we searched PubMed, Scopus, Web of Science, and Google Scholar databases using appropriate MESH terms until July 2022. All observational studies which assessed the ABO blood group frequency distribution and the association between ABO and CC were included. The Risk of Bias Assessment tool was used to assess the quality of studies. A random model was used to estimate the odds ratio (OR). The Egger test was used to assess the publication bias.
resultsOverall,14 studies (413,132 patients) were included. According to the pooled estimation, blood groups A, B, AB, and O frequency in patients with CC were 37%,18%,9%, and 31%, respectively. The OR of CC in people with the A blood group was higher than in the other groups (OR: 1.11, 95% CI:1.03,1.19, P:0.001). In contrast, the OR of CC in people with the O blood group was significantly lower than in other blood groups (OR: 0.93, 95% CI:0.83,0.97, P:0.001). No significant relationship was observed for B and AB blood groups with CC.
conclusionsThis Meta-analysis showed that blood group type A has a greater risk of developing CC, while blood group type O was associated with lower chances of CC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.