Evidence map›Paper›PMID 37642030›Full record

ArticleJournal of the American Heart Association2023

Human Milk Feeding and Direct Breastfeeding Improve Outcomes for Infants With Single Ventricle Congenital Heart Disease: Propensity Score-Matched Analysis of the NPC-QIC Registry.

Kristin M Elgersma, Julian Wolfson, Jayne A Fulkerson, Michael K Georgieff, Wendy S Looman, Diane L Spatz, Kavisha M Shah, Karen Uzark, Anne Chevalier McKechnie

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Human milk and breastfeeding at the first oral feed for infants with critical congenital heart disease: a multi-institutional study.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Article
  7. Improving preoperative enteral feeding for newborns with congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kristin M ElgersmaUniversity of Minnesota School of Nursing Minneapolis MN USA.ORCID 0000-0001-6559-0812
Julian WolfsonDivision of Biostatistics University of Minnesota School of Public Health Minneapolis MN USA.ORCID 0000-0002-2032-0875
Jayne A FulkersonUniversity of Minnesota School of Nursing Minneapolis MN USA.ORCID 0000-0002-2110-498X
Michael K GeorgieffDepartment of Pediatrics University of Minnesota Medical School Minneapolis MN USA.
Wendy S LoomanUniversity of Minnesota School of Nursing Minneapolis MN USA.ORCID 0000-0003-4608-4898
Diane L SpatzUniversity of Pennsylvania School of Nursing Philadelphia PA USA.ORCID 0000-0001-7316-6616
Kavisha M ShahDepartment of Pediatrics University of Minnesota Medical School Minneapolis MN USA.
Karen UzarkDivision of Cardiac Surgery University of Michigan Medical School Ann Arbor MI USA.ORCID 0000-0002-7303-7635
Anne Chevalier McKechnieUniversity of Minnesota School of Nursing Minneapolis MN USA.ORCID 0000-0002-1210-3379
University of Minnesota · USChildren's Hospital of Philadelphia · USUniversity of Michigan · US

Funding

Human Milk and Direct Breastfeeding for Infants with Single Ventricle Congenital Heart Disease: An Analysis of Prevalence, Supportive and Limiting Factors, and Impact on Key OutcomesF31NR020577 · NINR · UNIVERSITY OF MINNESOTA · PI ELGERSMA, KRISTIN M · 2022 to 2022
$49k
NINR NIH HHS F31 NR020577
6 · The paper itself

Abstract

Background Infants with single ventricle congenital heart disease undergo 3 staged surgeries/interventions, with risk for morbidity and mortality. We estimated the effect of human milk (HM) and direct breastfeeding on outcomes including necrotizing enterocolitis, infection-related complications, length of stay, and mortality. Methods and Results We analyzed the National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC) registry (2016-2021), examining HM/breastfeeding groups during stage 1 and stage 2 palliations. We calculated propensity scores for feeding exposures, then fitted Poisson and logistic regression models to compare outcomes between propensity-matched cohorts. Participants included 2491 infants (68 sites). Estimates for all outcomes were better in HM/breastfeeding groups. Infants fed exclusive HM before stage 1 palliation (S1P) had lower odds of preoperative necrotizing enterocolitis (odds ratio [OR], 0.37 [95% CI, 0.17-0.84];

Indexed as

CardiologyEnterocolitis, NecrotizingHeart Defects, CongenitalUniventricular HeartBreast FeedingChildFemaleHumansInfantInfant, NewbornMilk, HumanPropensity ScoreQuality ImprovementRegistriesbreast feedingcongenital heart defectshuman milkhypoplastic left heart syndromeinfant

Identifiers

PMID37642030
PMCPMC10547322
OpenAlexW4386245928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.