Evidence map›Paper›PMID 37641936›Full record

ArticleMolecules and cells2023

Avenanthramide-C Shows Potential to Alleviate Gingival Inflammation and Alveolar Bone Loss in Experimental Periodontitis.

Su-Jin Kim, Se Hui Lee, Binh Do Quang, Thanh-Tam Tran, Young-Gwon Kim, Jun Ko, Weon-Young Choi, Sun Young Lee, Je-Hwang Ryu

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Su-Jin KimDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0009-0002-9641-7531
Se Hui LeeDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0000-0002-9102-7115
Binh Do QuangDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0009-0001-7011-739X
Thanh-Tam TranDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0000-0002-3030-2224
Young-Gwon KimDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0009-0000-8085-7319
Jun KoDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0009-0003-7114-9152
Weon-Young ChoiDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0009-0005-7520-3974
Sun Young LeeDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0000-0003-1188-8896
Je-Hwang RyuDepartment of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Korea.ORCID https://orcid.org/0000-0002-8708-8943
Chonnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease is a chronic inflammatory disease that leads to the gradual destruction of the supporting structures of the teeth including gums, periodontal ligaments, alveolar bone, and root cementum. Recently, interests in alleviating symptoms of periodontitis (PD) using natural compounds is increasing. Avenanthramide-C (Avn-C) is a polyphenol found only in oats. It is known to exhibit various biological properties. To date, the effect of Avn-C on PD pathogenesis has not been confirmed. Therefore, this study aimed to verify the protective effects of Avn-C on periodontal inflammation and subsequent alveolar bone erosion

Indexed as

Alveolar Bone LossPeriodontitisAnimalsHumansInflammationInterleukin-6Miceortho-AminobenzoatesTumor Necrosis Factor-alphaavenanthramide-2CInterleukin-6ortho-AminobenzoatesTumor Necrosis Factor-alphaalveolar bone lossavenanthramide-Cgingival fibroblastsinflammationperiodontitis

Identifiers

PMID37641936
PMCPMC10590710
OpenAlexW4386251942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.