Evidence map›Paper›PMID 37641734›Full record

ArticleInternational journal of organ transplantation medicine2022

Current Situation and Prognostic Evolution of Combined Heart-lung Transplantation in a European Union Country.

R Lopez-Vilella, M Gomez Bueno, F Gonzalez Vflchez, A Sole Jover, R Laporta Hernandez, R Vicente Guillen, A I Gonzalez Roman, I Sanchez-Lazaro, F Hernandez Perez, G Sales Badfa and 6 more

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In one paragraph

Article in International journal of organ transplantation medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

R Lopez-VilellaHeart Failure and Transplantation Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
M Gomez BuenoCardiology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
F Gonzalez VflchezMarques de Valdecilla University Hospital, Santander, Spain.
A Sole JoverLung Transplant Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
R Laporta HernandezPneumology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
R Vicente GuillenAnesthesiology and Resuscitation Department, La Fe University and Polytechnic Hospital, Valencia, Spain.
A I Gonzalez RomanAnesthesiology and Resuscitation Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
I Sanchez-LazaroHeart Failure and Transplantation Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
F Hernandez PerezCardiology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
G Sales BadfaLung Transplant Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
M D M Cordoba PelaezThoracic Surgery Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
S Torregrosa PuertaCardiac Surgery Department, Hospital Universitario y Politécnico La Fe, Valencia, Espana.
A Forteza GilCardiac Surgery Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
L Martinez DolzCardiology Department, La Fe University and Polytechnic Hospital, Valencia, Spain.
J Segovia CuberoCardiology Department, Puerta de Hierro University Hospital, Majadahonda, Madrid, Spain.
L Almenar BonetHeart Failure and Transplantation Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
Hospital Universitari i Politècnic La Fe · ESHospital Universitario Puerta de Hierro Majadahonda · ESInstituto de Salud Carlos III · ESMarqués de Valdecilla University Hospital · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aims to evaluate the entire experience in heart-lung transplantation (HLTx) in a country of the European Union with 47 million inhabitants according to the etiologies that motivated the procedure. Methods: A retrospective study on 1,751 consecutive transplants (HLTx: 78) was performed from 1990 to 2020 in two centers. Overall survival, adjusted for clinical profile and etiological subgroups, was compared. 7 subgroups were considered: 1) Cardiomyopathy with pulmonary hypertension (CM + PH). 2) Eisenmenger syndrome. 3) Congenital heart disease (CHD). 4) Idiopathic pulmonary arterial hypertension (IPAH). 5) Cystic fibrosis. 6) Chronic obstructive pulmonary disease (COPD)/Emphysema. 7) Diffuse interstitial lung disease (ILD). Results: Early mortality was 44% and that of the rest of the follow-up was 31%. There were differences between HTLx and HTx in survival, also comparing groups with a similar clinical profile with propensity score (p= 0.04). Median survival was low in CM + PH (18 days), ILD (29 days) and CHD (114 days), intermediate in Eisenmenger syndrome (600 days), and longer in IPAH, COPD/Emphysema and cystic fibrosis. Conclusion: HLTx has a high mortality. The etiological analysis is of the utmost interest to make the most of the organs and improve survival.

Indexed as

EtiologyHeart-lung transplantationHeart transplantationSurvival

Identifiers

PMID37641734
PMCPMC10460527
OpenAlexW4386271991

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.