ReviewMedical hypothesis, discovery & innovation ophthalmology journal2021
Update on indications, complications, and outcomes of scleral contact lenses.
Review in Medical hypothesis, discovery & innovation ophthalmology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Prospective pilot randomized controlled study of mini-scleral lenses versus rigid gas permeable lenses in irregular cornea with dry eye.Scientific reports · 2026Trial
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
- Article
- Long-term impact of scleral contact lens use on endothelial cell density in patients with moderate to advanced keratoconus.BMC ophthalmology · 2026Article
- Clinical Experience with Scleral Lens Wear After Corneal Cross-Linking in Keratoconus: Longitudinal Keratometric Outcomes.Journal of clinical medicine · 2026Article
- Advances in the Medical Management of Pediatric Blepharokeratoconjunctivitis.Advances in therapy · 2026Review
- Avoiding Surgery: Successful Management of a Patient With Severe Keratoconus Using Scleral Contact Lenses.Cureus · 2025Article
- Pilot Study Evaluating the Early Clinical Outcomes Obtained with a Novel, Customized, Multifocal Corneo-Scleral Contact Lens for Presbyopia Correction.Life (Basel, Switzerland) · 2025Article
- Two cases of therapeutic scleral lenses for KID syndrome.American journal of ophthalmology case reports · 2025Article
- Short-Term Efficacy and Safety of Scleral Lenses in the Management of Severe Dry Eye in a Chinese Population.Journal of clinical medicine · 2025Article
- Bibliometric and visual analysis of scleral contact lenses: global characteristics and research trends from 1976 to 2023.International journal of ophthalmology · 2025Article
- Scleral lenses and PROSE: indications, complications, and future challenges.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Review
- Sustained descemetocele management with Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment.American journal of ophthalmology case reports · 2024Article
- Impact of Scleral Lenses on Visual Acuity and Ocular Aberrations in Corneal Ectasia: A Comprehensive Review.Journal of personalized medicine · 2024Review
- Ocular surface lesions in clinical grades of Bell's phenomenon.Medical hypothesis, discovery & innovation ophthalmology journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The role of scleral contact lenses (SCLs) has increasingly expanded since the first lens was fitted more than a century ago. While it was initially prescribed for the management of severely compromised corneas, the indications for modern SCL use have expanded to include less severe diseases. In this review, we aimed to provide an up-to-date overview of the current indications, complications, and outcomes for the various types of SCLs. Methods: In this narrative review, we thoroughly searched the PubMed/MEDLINE database for literature published from January 1980 to November 2021. Only relevant up-to-date English references were included. Furthermore, the figures in this manuscript were derived from our unit's patient documentation. Results: Currently, SCLs can successfully be used to manage ocular surface diseases, visually rehabilitate irregular corneas, and correct irregular refractive errors. Although newer materials have yielded the same visual outcomes with fewer complications, these consequences still occur in approximately one-third of contact lens wearers, including difficulties in insertion and/or removal, discomfort or pain, and developing either halos, blurriness, or haze. Even though most of these complications are minor and can be easily treated, a good practice is essential to avoid sight-threatening complications such as microbial keratitis. Conclusions: SCLs are indispensable in ophthalmic clinics. The development of better-quality SCLs has increased the number of indications and improved the achievable visual rehabilitation. The future of developing improvements in SCL design, materials, and fit, and the expansion of their indication range is promising.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.