Evidence map›Paper›PMID 37641591›Full record

ReviewRegenerative biomaterials2023

Nature-inspired nanocarriers for improving drug therapy of atherosclerosis.

Weihong Ji, Yuanxing Zhang, Yuanru Deng, Changyong Li, Ranjith Kumar Kankala, Aizheng Chen

Open access · goldAbstract readReview
In one paragraph

Review in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Polymeric Nanomaterials for Atherosclerosis Diagnosis and Treatment.Polymer science & technology (Washington, D.C.) · 2025
    Review
  10. Review
  11. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Weihong JiInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 361021, PR China.
Yuanxing ZhangThe Institute of Forensic Science, Xiamen Public Security Bureau, Xiamen, Fujian 361104, PR China.
Yuanru DengInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 361021, PR China.
Changyong LiInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 361021, PR China.
Ranjith Kumar KankalaInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 361021, PR China.ORCID https://orcid.org/0000-0003-4081-9179
Aizheng ChenInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian 361021, PR China.ORCID https://orcid.org/0000-0002-5840-3406
Huaqiao University · CNInstitute of Forensic Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) has emerged as one of the prevalent arterial vascular diseases characterized by plaque and inflammation, primarily causing disability and mortality globally. Drug therapy remains the main treatment for AS. However, a series of obstacles hinder effective drug delivery. Nature, from natural micro-/nano-structural biological particles like natural cells and extracellular vesicles to the distinctions between the normal and pathological microenvironment, offers compelling solutions for efficient drug delivery. Nature-inspired nanocarriers of synthetic stimulus-responsive materials and natural components, such as lipids, proteins and membrane structures, have emerged as promising candidates for fulfilling drug delivery needs. These nanocarriers offer several advantages, including prolonged blood circulation, targeted plaque delivery, targeted specific cells delivery and controlled drug release at the action site. In this review, we discuss the nature-inspired nanocarriers which leverage the natural properties of cells or the microenvironment to improve atherosclerotic drug therapy. Finally, we provide an overview of the challenges and opportunities of applying these innovative nature-inspired nanocarriers.

Indexed as

atherosclerosisdrug deliverymembrane-coatingnature-inspired nanocarriersstimuli-responsive

Identifiers

PMID37641591
PMCPMC10460486
OpenAlexW4385755594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.