ArticleEuropean stroke journal2023
Sex differences in associations between creatinine and cystatin C-based kidney function measures with stroke and major bleeding.
Article in European stroke journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Relationship between serum cystatin C and long-term mortality in patients with self-reported COPD: evidence from two large population-based surveys.BMJ open respiratory research · 2026Article
- Association Between Renal Dysfunction and Cerebral Small Vessel Disease: A Prospective Cohort Study From the UK Biobank.CNS neuroscience & therapeutics · 2026Article
- Association of Differences in Cystatin C- and Creatinine-Based Estimated Glomerular Filtration Rate With Prevalence and Incidence of Stroke.Journal of the American Heart Association · 2025Article
- A comprehensive analysis of stroke risk factors and development of a predictive model using machine learning approaches.Molecular genetics and genomics : MGG · 2025Article
- Prediction of cardiovascular events and all-cause mortality using race and race-free estimated glomerular filtration rate in African Americans: the Jackson Heart Study.Frontiers in medicine · 2024Article
- Serum cystatin C and stroke risk: a national cohort and Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Cardiovascular disease in older women with CKD.Clinical kidney journal · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeWe sought to explore whether adding kidney function biomarkers based on creatinine (eGFR
methodWe included participants from the UK Biobank who had not had a previous ischaemic or haemorrhagic stroke or major bleeding episode, and who had kidney function measures available at baseline. Cause-specific Cox proportional hazards models tested associations between eGFR
findingsAmong 452,879 eligible participants, 246,244 (54.4%) were women. Over 11.5 (IQR 10.8-12.2) years, there were 3706 ischaemic strokes, 795 haemorrhagic strokes, 26,025 major bleeding events and 28,851 deaths. eGFR DISCUSSION: To a greater degree than is seen in men, eGFR
conclusionEnhanced measurement of cystatin C may improve risk stratification for ischaemic stroke and major bleeding and clinical treatment decisions in a general population setting, particularly for women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.