Evidence map›Paper›PMID 37641050›Full record

SynthesisJournal of orthopaedic surgery and research2023

Evidence on risk factors for knee osteoarthritis in middle-older aged: a systematic review and meta analysis.

Yawei Dong, Yan Yan, Jun Zhou, Qiujun Zhou, Hongyu Wei

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721897 (Effectiveness of a Prehabilitation Program on Clinical, Functional and Psychological Variables in Candidates for Hip or Knee Arthroplasty Surgery.), which is not on this map. Cited by 69 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 12 pooled it
19.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721897 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of a Prehabilitation Program on Clinical, Functional and Psychological Variables in Candidates for Hip or Knee Arthroplasty Surgery.

TypeinterventionalSponsorUniversity of JaénRan2025 to 2027Enrolled44ConditionsPrehabilitation, Knee Osteoarthritis, Hip Osteoarthritis, Physical Therapy ModalitiesArmsPrehabilitation Program, Non prehabilitation Program
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 12 syntheses or guidelines pooled it, 80 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yawei Dong *Beijing University of Chinese Medicine, Beijing, China.
Yan Yan *Beijing University of Chinese Medicine, Beijing, China.
Jun Zhou *Beijing University of Chinese Medicine, Beijing, China.
Qiujun ZhouDepartment of First Clinical Medical College, Zhejiang Chinese Medical University, No. 2, Sakura Garden East Street, Chaoyang District, Beijing, China.
Hongyu WeiDepartment of Orthopaedic Surgery, China-Japan Friendship Hospital, Beijing, China. doctor_wei@126.com.
Beijing University of Chinese Medicine · CNChina-Japan Friendship Hospital · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis review was made to identify the risk factors for knee osteoarthritis (KOA) in middle-older aged (≥ 40 years), and to provide the newest evidence for the prevention of KOA.

methodCohort study and case-control study of the risk factors of KOA was included from Pubmed, Web of Science, Ovid Technologies, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang Database, SinoMed from their inceptions to July 2023. Two authors independently screened the literature and extracted data. Assessment of quality was implemented according to Agency for Healthcare Research and Quality (AHRQ) and Newcastle-Ottawa Quality Assessment Scale. Meta-analysis was performed using RevMan 5.3 software.

results3597 papers were identified from the seven databases and 29 papers containing 60,354 participants were included in this review. Meta-analysis was performed for 14 risk factors, and 7 of these were statistical significance (P < 0.05). The risk factors which were analyzed in this review included trauma history in knee (1.37 [95% CI 1.03-1.82], P = 0.030), body mass index (BMI) ≥ 24 kg/m

conclusionThe risk factors analyzed in this review included trauma history in knee, overweight or obesity, gender (female), age ≥ 40 and the protective factors included more exercise and a high school or an university education background.

Indexed as

Osteoarthritis, KneeAgedCase-Control StudiesCohort StudiesFemaleHumansKnee JointMiddle AgedRisk FactorsUnited StatesKnee osteoarthritisMeta-analysisMiddle-older agedRisk factors

Identifiers

PMID37641050
PMCPMC10464102
OpenAlexW4386252907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.