SynthesisBMC geriatrics2023
Comparative efficacy of 24 exercise types on postural instability in adults with Parkinson's disease: a systematic review and network meta-analysis.
Synthesis in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Optimal dose and type of exercise improve the overall balance in adults with Parkinson's disease: a systematic review and Bayesian network meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Effects of breathing training on walking ability and quality of life in patients with multiple sclerosis: systematic review and meta-analysis of randomized controlled trials.Frontiers in immunology · 2025Pooled it
- Optimal dosage ranges of various exercise types for enhancing timed up and go performance in Parkinson's disease patients: a systematic review and Bayesian network meta-analysis.Frontiers in aging neuroscience · 2024Pooled it
- Acute and chronic effects of stretching on balance: a systematic review with multilevel meta-analysis.Frontiers in medicine · 2024Pooled it
- Stochastic resonance stimulation effect on stability during walking in people with Parkinson disease.International biomechanics · 2025Trial
- Mapping motor exercise interventions in Parkinson's disease: a scoping review of intervention types, outcomes, adherence, and dropout.Frontiers in sports and active living · 2026Review
- Qualitative Assessment of Network Meta-Analyses of Exercise Therapy for Parkinson's Disease: A Scoping Review.Cureus · 2025Review
- The Effects of Pilates in Parkinson's Disease-A Narrative Review.Life (Basel, Switzerland) · 2025Review
- AquaDualPark Study - Effects of Aquatic and Land-Based Dual-Task Exercise Program on Motor and Cognitive Functions of People With Parkinson's Disease: Protocol for a Randomized Clinical Trial.Health services insights · 2025Article
- Comparative effectiveness of different modes of exercise interventions in diabetics with frailty in China: a systematic review and a network meta-analysis.Diabetology & metabolic syndrome · 2024Review
- Association of time spent outdoors with the risk of Parkinson's disease: a prospective cohort study of 329,359 participants.BMC neurology · 2024Article
- Research progress on the application of anti-gravity treadmill in the rehabilitation of Parkinson's disease patients: a mini review.Frontiers in neurology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare, rank and evaluate the 24 exercise types that improve postural instability in patients with Parkinson's disease (PD).
methodsWe searched the data in PubMed, MEDLINE, Embase, PsycINFO, Cochrane library, and Web of Science from their inception date to January 23, 2023. Randomized controlled trials (RCTs) that aimed at determining the effectiveness of physical activity interventions on postural instability in adults with PD. This review focused on different balance outcome categories: (a) balance test batteries (BBS); (b) static steady-state balance (sSSB); (c) dynamic steady-state balance (dSSB); (d) proactive balance (PB); (e) reactive balance (RB).
resultsAmong 10,474 records, 199 studies (patients = 9523) were eligible for qualitative synthesis. The random-effects NMA model revealed that the following exercise training modalities had the highest p score of being best when compared with control group: body-weight support treadmill training (BWS_TT) for BBS (p score = 0.97; pooled standardised mean difference (95% CI): 1.56 (0.72 to 2.39)) and dSSB (1.00; 1.53 (1.07 to 2.00)), aquatic exercise (AQE) for sSSB (0.85; 0.94 (0.33 to 1.54)), Pilates for PB (0.95; 1.42 (0.59 to 2.26)). Balance and gait training with the external cue or attention (BGT_ECA) and robotic assisted gait balance (RA_GT) had similar superior effects in improving RB. The confidence in evidence was often low according to Confidence in Network Meta-Analysis.
conclusionsThere is low quality evidence that BWS_TT, AQE, Pilates, BGT_ECA and RA_GT are possibly the most effective treatments, pending outcome of interest, for adults with PD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.