Evidence map›Paper›PMID 37640952›Full record

ArticleSurgical endoscopy2023

Time required for indocyanine green fluorescence emission for evaluating bowel perfusion in left-sided colon and rectal cancer surgery.

Chie Hagiwara, Taiga Wakabayashi, Atsuko Tsutsui, Junichi Sakamoto, Shohei Fujita, Yoshiki Fujiyama, Nobuhiko Okamoto, Kenji Omura, Takeshi Naitoh, Go Wakabayashi

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chie HagiwaraDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan. hagiwara.ch@ach.or.jp.ORCID http://orcid.org/0009-0000-9945-7737
Taiga WakabayashiDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Atsuko TsutsuiDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Junichi SakamotoDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Shohei FujitaDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Yoshiki FujiyamaDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Nobuhiko OkamotoDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Kenji OmuraDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Takeshi NaitohDepartment of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.
Go WakabayashiDepartment of Surgery, Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo-city, Saitama, 362-8588, Japan.
Hakodate Central General Hospital · JPKitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndocyanine green fluorescence imaging (ICG-FI) has been reported to be useful in reducing the incidence of anastomotic leakage (AL) in colectomy. This study aimed to investigate the correlation between the required time for ICG fluorescence emission and AL in left-sided colon and rectal cancer surgery using the double-stapling technique (DST) anastomosis.

methodsThis retrospective study included 217 patients with colorectal cancer who underwent left-sided colon and rectal surgery using ICG-FI-based perfusion assessment at our department between November 2018 and July 2022. We recorded the time required to achieve maximum fluorescence emission after ICG systemic injection and assessed its correlation with the occurrence of AL.

resultsAmong 217 patients, AL occurred in 21 patients (9.7%). The median time from ICG administration to maximum fluorescence emission was 32 s (range 25-58 s) in the AL group and 28 s (range 10-45 s) in the non-AL group (p < 0.001). The cut-off value for the presence of AL obtained from the ROC curve was 31 s. In 58 patients with a required time for ICG fluorescence of 31 s or longer, the following risk factors for AL were identified: low preoperative albumin [3.4 mg/dl (range 2.6-4.4) vs. 3.9 mg/dl (range 2.6-4.9), p = 0.016], absence of preoperative mechanical bowel preparation (53.8% vs. 91.1%, p = 0.005), obstructive tumor (61.5% vs. 17.8%, p = 0.004), and larger tumor diameter [65 mm (range 40-90) vs. 35 mm (range 4.0-100), p < 0.001].

conclusionThe time required for ICG fluorescence emission was associated with AL.

Indexed as

Colorectal NeoplasmsLaparoscopyRectal NeoplasmsAnastomosis, SurgicalAnastomotic LeakColectomyColoring AgentsHumansIndocyanine GreenPerfusionRetrospective StudiesColoring AgentsIndocyanine GreenAnastomotic leakageBowel perfusionColorectal cancerDouble stapling techniqueICGIndocyanine green

Identifiers

PMID37640952
OpenAlexW4386212730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.