Evidence map›Paper›PMID 37640908›Full record

ArticleNature nanotechnology2023

Site-directed placement of three-dimensional DNA origami.

Irina V Martynenko, Elisabeth Erber, Veronika Ruider, Mihir Dass, Gregor Posnjak, Xin Yin, Philipp Altpeter, Tim Liedl

Abstract read
In one paragraph

Article in Nature nanotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Tunable Patterning of DNA Origami on Surfaces Using Steric Brushes.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. DNA moiré superlattices.Nature nanotechnology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. DNA-based computation for multiple biomarkers.Nature biomedical engineering · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irina V MartynenkoFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany. irina.martynenko@physik.lmu.de.ORCID 0000-0001-5239-3043
Elisabeth ErberFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Veronika RuiderFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Mihir DassFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Gregor PosnjakFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Xin YinFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Philipp AltpeterFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany.
Tim LiedlFaculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany. tim.liedl@physik.lmu.de.ORCID 0000-0002-0040-0173

Funding

European Research Council 818635
6 · The paper itself

Abstract

The combination of lithographic methods with two-dimensional DNA origami self-assembly has led, among others, to the development of photonic crystal cavity arrays and the exploration of sensing nanoarrays where molecular devices are patterned on the sub-micrometre scale. Here we extend this concept to the third dimension by mounting three-dimensional DNA origami onto nanopatterned substrates, followed by silicification to provide hybrid DNA-silica structures exhibiting mechanical and chemical stability and achieving feature sizes in the sub-10-nm regime. Our versatile and scalable method relying on self-assembly at ambient temperatures offers the potential to three-dimensionally position any inorganic and organic components compatible with DNA origami nanoarchitecture, demonstrated here with gold nanoparticles. This way of nanotexturing could provide a route for the low-cost production of complex and three-dimensionally patterned surfaces and integrated devices designed on the molecular level and reaching macroscopic dimensions.

Indexed as

Metal NanoparticlesNanostructuresDNAGoldNanotechnologyNucleic Acid ConformationSilicon DioxideDNAGoldSilicon Dioxide

Identifiers

PMID37640908
PMCPMC7616159

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.