Evidence map›Paper›PMID 37640517›Full record

ArticleRMD open2023

Prevalence and distribution of vascular calcifications at CT scan in patients with and without large vessel vasculitis: a matched cross-sectional study.

Giulia Besutti, Chiara Marvisi, Pamela Mancuso, Roberto Farì, Filippo Monelli, Matteo Revelli, Rexhep Durmo, Elena Galli, Francesco Muratore, Lucia Spaggiari and 5 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Giulia Besutti *Radiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-5319-5495
Chiara Marvisi *Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0001-7027-1410
Pamela MancusoEpidemiology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Roberto FarìRadiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy roberto.fari@ausl.re.it.
Filippo MonelliRadiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Matteo RevelliRadiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Rexhep DurmoClinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.
Elena GalliRheumatology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Francesco MuratoreRheumatology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0003-0362-2668
Lucia SpaggiariRadiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Marta OttoneEpidemiology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Stefano LuminariDepartment of Surgery, Medicine, Dentistry and Morphological Sciences with interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Pierpaolo PattaciniRadiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Paolo Giorgi RossiEpidemiology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Carlo SalvaraniRheumatology Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
University of Modena and Reggio Emilia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to compare the prevalence, entity and local distribution of arterial wall calcifications evaluated on CT scans in patients with large vessel vasculitis (LVV) and patients with lymphoma as reference for the population without LVV.

methodsAll consecutive patients diagnosed with LVVs with available baseline positron emission tomography-CT (PET-CT) scan performed between 2007 and 2019 were included; non-LVV patients were lymphoma patients matched by age (±5 years), sex and year of baseline PET-CT (≤2013; >2013). CT images derived from baseline PET-CT scans of both patient groups were retrospectively reviewed by a single radiologist who, after setting a threshold of minimum 130 Hounsfield units, semiautomatically computed vascular calcifications in three separate locations (coronaries, thoracic and abdominal arteries), quantified as Agatston and volume scores.

resultsA total of 266 patients were included. Abdominal artery calcifications were equally distributed (mean volume 3220 in LVVs and 2712 in lymphomas). Being in the LVVs group was associated with the presence of thoracic calcifications after adjusting by age and year of diagnosis (OR 4.13, 95% CI 1.35 to 12.66; p=0.013). Similarly, LVVs group was significantly associated with the volume score in the thoracic arteries (p=0.048). In patients >50 years old, calcifications in the coronaries were more extended in non-LVV patients (p=0.027 for volume).

conclusionWhen compared with patients without LVVs, LVVs patients have higher calcifications in the thoracic arteries, but not in coronary and abdominal arteries.

Indexed as

Vascular CalcificationVasculitisCross-Sectional StudiesHumansMiddle AgedPositron Emission Tomography Computed TomographyPrevalenceRetrospective StudiesTomography, X-Ray Computedatherosclerosisgiant cell arteritissystemic vasculitis

Identifiers

PMID37640517
PMCPMC10462964
OpenAlexW4386227119

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.