Evidence map›Paper›PMID 37640449›Full record

ArticleLife science alliance2023

Incomplete activation of

Shunya Ihashi, Mizuto Hamanaka, Masaya Kaji, Ryunosuke Mori, Shuntaro Nishizaki, Miki Mori, Yuma Imasato, Kimiko Inoue, Shogo Matoba, Narumi Ogonuki and 7 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Probing RNA-protein interactions in the early mouse embryo.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Shunya IhashiLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Mizuto HamanakaLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Masaya KajiLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Ryunosuke MoriLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Shuntaro NishizakiLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Miki MoriLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Yuma ImasatoLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Kimiko InoueBioresource Engineering Division, RIKEN Bioresource Research Center, Tsukuba, Japan.
Shogo MatobaBioresource Engineering Division, RIKEN Bioresource Research Center, Tsukuba, Japan.
Narumi OgonukiBioresource Engineering Division, RIKEN Bioresource Research Center, Tsukuba, Japan.
Atsushi TakasuLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Misaki NakamuraLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Kazuya MatsumotoLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan.
Masayuki AnzaiInstitute of Advanced Technology, Kindai University, Wakayama, Japan.
Atsuo OguraBioresource Engineering Division, RIKEN Bioresource Research Center, Tsukuba, Japan.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Suita, Japan.
Kei MiyamotoLaboratory of Molecular Developmental Biology, Faculty of Biology-Oriented Science and Technology, Kindai University, Wakayama, Japan kmiyamo@waka.kindai.ac.jp.ORCID https://orcid.org/0000-0003-2912-6777
Kindai University · JPRIKEN BioResource Research Center · JPUniversity of Tsukuba · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiated cell nuclei can be reprogrammed after nuclear transfer (NT) to oocytes and the produced NT embryos can give rise to cloned animals. However, development of NT embryos is often hampered by recurrent reprogramming failures, including the incomplete activation of developmental genes, yet specific genes responsible for the arrest of NT embryos are not well understood. Here, we searched for developmentally important genes among the reprogramming-resistant H3K9me3-repressed genes and identified

Indexed as

ApoptosisBlastocystAnimalsCell DifferentiationCell NucleusGene Knockout TechniquesMice

Identifiers

PMID37640449
PMCPMC10462978
OpenAlexW4386217736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.