Evidence map›Paper›PMID 37640155›Full record

ArticleJournal of global antimicrobial resistance2023

Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore.

Zhilian Huang, Mithun Mohan George, Yi-Roe Tan, Karthiga Natarajan, Emily Devasagayam, Evonne Tay, Abi Manesh, George M Varghese, Ooriapadickal Cherian Abraham, Anand Zachariah and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of global antimicrobial resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  11. Generative artificial intelligence in otolaryngology-head and neck surgery editorial: be an actor of the future or follower.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Zhilian HuangInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.
Mithun Mohan GeorgeDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Yi-Roe TanInternational Digital Health & AI Research Collaborative (I-DAIR), Geneva, Switzerland.
Karthiga NatarajanInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.
Emily DevasagayamDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Evonne TayInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.
Abi ManeshDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
George M VargheseDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Ooriapadickal Cherian AbrahamDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Anand ZachariahDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Peiling YapInternational Digital Health & AI Research Collaborative (I-DAIR), Geneva, Switzerland.
Dorothy LallDepartment of Community Health, Christian Medical College Vellore - Chittoor Campus, Andhra Pradesh, India. Electronic address: dorothy.lall@cmcvellore.ac.in.
Angela ChowInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address: Angela_Chow@ttsh.com.sg.
Christian Medical College, Vellore · INTan Tock Seng Hospital · SGNanyang Technological University · SG

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesArtificial intelligence (AI)-driven clinical decision support systems (CDSSs) can augment antibiotic decision-making capabilities, but physicians' hesitancy in adopting them may undermine their utility. We conducted a cross-country comparison of physician perceptions on the barriers and facilitators in accepting an AI-enabled CDSS for antibiotic prescribing.

methodsWe conducted in-depth interviews with physicians from the National Centre for Infectious Diseases (NCID), Singapore, and Christian Medical College Vellore (CMCV), India, between April and December 2022. Our semi-structured in-depth interview guides were anchored on Venkatesh's UTAUT model. We used clinical vignettes to illustrate the application of AI in clinical decision support for antibiotic prescribing and explore medico-legal concerns.

resultsMost NCID physicians felt that an AI-enabled CDSS could facilitate antibiotic prescribing, while most CMCV physicians were sceptical about the tool's utility. The hesitancy in adopting an AI-enabled CDSS stems from concerns about the lack of validated and successful examples, fear of losing autonomy and clinical skills, difficulty of use, and impediment in work efficiency. Physicians from both sites felt that a user-friendly interface, integration with workflow, transparency of output, a guiding medico-legal framework, and training and technical support would improve the uptake of an AI-enabled CDSS.

conclusionIn conclusion, the acceptance of AI-enabled CDSSs depends on the physician's confidence with the tool's recommendations, perceived ease of use, familiarity with AI, the organisation's digital culture and support, and the presence of medico-legal governance of AI. Progressive implementation and continuous feedback are essential to allay scepticism around the utility of AI-enabled CDSSs.

Indexed as

Decision Support Systems, ClinicalPhysiciansAnti-Bacterial AgentsArtificial IntelligenceHumansIndiaSingaporeAnti-Bacterial AgentsAntibiotic prescribingAntimicrobial resistanceArtificial intelligenceClinical decision support system

Identifiers

PMID37640155
PMCPMC10684720
OpenAlexW4386196141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.