Evidence map›Paper›PMID 37639198›Full record

ReviewMolecular and cellular biochemistry2024

LncRNAs in Kawasaki disease and Henoch-Schönlein purpura: mechanisms and clinical applications.

Kangping Yang, Jiayao Tang, Haoying Li, Hejin Zhang, Jiatong Ding, Zelin Li, Jinghua Luo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kangping Yang *Department of Pediatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. Yangkangping0913@163.com.
Jiayao Tang *School of Pharmacy, Nanchang University, Nanchang, China.
Haoying Li *Queen Mary School of Nanchang University, Nanchang, China.
Hejin ZhangThe Second Clinical Medical College of Nanchang University, Nanchang, China.
Jiatong DingThe Second Clinical Medical College of Nanchang University, Nanchang, China.
Zelin LiThe First Clinical Medical College of Nanchang University, Nanchang, China.
Jinghua LuoDepartment of Pediatrics, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. Ndefy11074@ncu.edu.cn.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CN

Funding

Natural Science Foundation of Jiangxi Province (20202BABL206024)
6 · The paper itself

Abstract

Kawasaki disease (KD) and Henoch-Schönlein purpura (HSP) are the two most predominant types of childhood vasculitis. In childhood vasculitis, factors such as lack of sensitive diagnostic indicators and adverse effects of drug therapy may cause multiorgan system involvement and complications and even death. Many studies suggest that long noncoding RNAs (lncRNAs) are involved in the mechanism of vasculitis development in children and can be used to diagnose or predict prognosis by lncRNAs. In existing drug therapies, lncRNAs are also involved in drug-mediated treatment mechanisms and are expected to improve drug toxicity. The aim of this review is to summarize the link between lncRNAs and the pathogenesis of KD and HSP. In addition, we review the potential applications of lncRNAs in multiple dimensions, such as diagnosis, treatment, and prognosis prediction. This review highlights that targeting lncRNAs may be a novel therapeutic strategy to improve and treat KD and HSP.

Indexed as

IgA VasculitisMucocutaneous Lymph Node SyndromeRNA, Long NoncodingHumansPrognosisRNA, Long NoncodingChildhood vasculitisHenoch-Schönlein purpura (HSP)Kawasaki disease (KD)LncRNATherapeutic strategy

Identifiers

PMID37639198
OpenAlexW4386209182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.