Evidence map›Paper›PMID 37638887›Full record

ReviewThe Journal of experimental medicine2023

Targeting helminths: The expanding world of type 2 immune effector mechanisms.

Rick M Maizels, William C Gause

Abstract readReview
In one paragraph

Review in The Journal of experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  16. Article
  17. Tuft cells in the intestine, immunity and beyond.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  18. Review
  19. Generation and repair of thymic epithelial cells.The Journal of experimental medicine · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rick M MaizelsWellcome Centre for Integrative Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.ORCID 0000-0003-3216-1944
William C GauseCenter for Immunity and Inflammation, Rutgers Biomedical Health Sciences Institute for Infectious and Inflammatory Diseases, New Jersey Medical School, Rutgers Biomedical Health Sciences, Newark, NJ, USA.ORCID 0000-0002-8062-4790

Funding

Protective and pathologic functions of macrophages induced by helminthsR01AI131634 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, SIRACUSA, MARK CHRISTOPHER · 2018 to 2022
$2.6M
Purinergic signaling in granuloma-forming Th2 immunityR01DK113790 · NIDDK · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GAUSE, WILLIAM CLARK, HASKO, GEORGE · 2017 to 2020
$1.9M
NIAID NIH HHS R01 AI131634NIDDK NIH HHS R01 DK113790Wellcome Trust 104111Wellcome Trust 219530
6 · The paper itself

Abstract

In this new review, Rick Maizels and Bill Gause summarize how type 2 immune responses combat helminth parasites through novel mechanisms, coordinating multiple innate and adaptive cell and molecular players that can eliminate infection and repair-resultant tissue damage.

Indexed as

HelminthiasisHelminthsAnimals

Identifiers

PMID37638887
PMCPMC10460967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.