ArticleFrontiers in neuroscience2023
Estimating axon radius using diffusion-relaxation MRI: calibrating a surface-based relaxation model with histology.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Disentangling pontine fiber geometry and microstructure in ARSACS using advanced MRI.NeuroImage. Clinical · 2026Article
- Investigating the Sensitivity of the Diffusion MRI Signal to Magnetization Transfer and Permeability via Monte-Carlo Simulations.Magnetic resonance in medicine · 2026Article
- The microstructure-weighted human connectome: network properties and structure-function correlations across spatial scales.bioRxiv : the preprint server for biology · 2026Article
- Multi-dimensional diffusion MRI at ultra-high gradient strength for mapping axonal architecture and microstructure in the primate brain.bioRxiv : the preprint server for biology · 2026Article
- Multi-modal Monte Carlo MRI simulator of tissue microstructure.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- MRI-scale histology validates spatial sensitivity of in-vivo MRI-based axon radius estimation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- TImaging neuroscience (Cambridge, Mass.) · 2025Article
- White matter microstructure of language pathways in non-verbal autism: insights from diffusion tensor imaging and myelin water imaging.Frontiers in human neuroscience · 2025Article
- Feasibility of brain intra-axonal microstructure imaging with ultrahigh B-encoding using MAGNUS ultra-high-performance gradients.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Pore size estimation in axon-mimicking microfibers with diffusion-relaxation MRI.Magnetic resonance in medicine · 2024Article
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Authors and funding
10 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately estimating the radius of axons in the human brain is challenging. Most axons in the brain have a radius below one micrometer, which falls below the sensitivity limit of dMRI signals even when using the most advanced human MRI scanners. Therefore, new MRI methods that are sensitive to small axon radii are needed. In this proof-of-concept investigation, we examine whether a surface-based axonal relaxation process could mediate a relationship between intra-axonal T
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.