Evidence map›Paper›PMID 37638247›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2021

Long-Term Outcomes in Complex Abdominal Wall Reconstruction Repaired With Absorbable Biologic Polymer Scaffold (Poly-4-Hydroxybutyrate).

Joseph F Buell, Alexandros N Flaris, Sukreet Raju, Adam Hauch, Michael Darden, Geoff G Parker

Abstract read
In one paragraph

Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Hernia mesh repair in immunocompromised patients: a comprehensive review.Hernia : the journal of hernias and abdominal wall surgery · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Clinical outcomes of oncologic hernia repair using Poly-4-Hydroxybutyrate (P4HB) mesh.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  9. Evaluating P4HB mesh in oncologic hernia repair: promise and perspective.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph F BuellFrom the Department of Surgery, Mission Health, HCA North Carolina, MAHEC, University of North Carolina, Asheville, NC.
Alexandros N FlarisDepartment of Surgery, Tulane University, New Orleans, LA.
Sukreet RajuDepartment of Surgery, Tulane University, New Orleans, LA.
Adam HauchDepartment of Surgery, University of California, San Diego, CA.
Michael DardenCarey Business School, Johns Hopkins University, Baltimore, MD.
Geoff G ParkerThayer School of Engineering, Dartmouth College, Hanover, NH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: After promising early outcomes in the use of absorbable biologic mesh for complex abdominal wall reconstruction, significant criticism has been raised over the longevity of these repairs after its 2-year resorption profile. Methods: This is the long-term (5-year) follow-up analysis of our initial experience with the absorbable polymer scaffold poly-4-hydroxybutyrate (P4HB) mesh compared with a consecutive contiguous group treated with porcine cadaveric mesh for complex abdominal wall reconstructions. Our clinical analysis was performed using Stata 14.2 and Excel 16.16.23. Results: After a 5-year follow-up period, the P4HB group (n = 31) experienced lower rates of reherniation (12.9% vs 38.1%; Conclusions: Our study identified the superior outcomes in clinical performance and a value-based benefit of absorbable biologic P4HB scaffold persisted after the 2-year resorption timeframe. Data analysis also confirmed the use of porcine cadaveric grafts independently contributed to the incidence of complications and recurrences.

Indexed as

abdominal wall reconstructionbiologic meshbiosynthetic meshpolymer mesh

Identifiers

PMID37638247
PMCPMC10455061

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.