Evidence map›Paper›PMID 37637848›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2023

Generalized Dystonia Due to a Pathogenic

Shakya Bhattacharjee, Monty A Silverdale, Michael Bonello, Julian Evans, Christopher Kobylecki

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shakya BhattacharjeeDepartment of Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK.ORCID 0000-0002-8493-3013
Monty A SilverdaleDepartment of Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK.ORCID 0000-0002-3295-6897
Michael BonelloDepartment of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.ORCID 0000-0002-0080-3976
Julian EvansDepartment of Neurosurgery, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Christopher KobyleckiDepartment of Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK.ORCID 0000-0002-7797-0756
Manchester Academic Health Science Centre · GBSalford Royal Hospital · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 21-year-old woman of south Asian origin presented with cervical dystonia which had progressed over the previous three years. Her symptoms started as writer's cramp since the age of seven years. She did not respond to medications and needed botulinum toxin injection for generalised dystonia. Subsequent whole genome sequencing revealed a likely pathogenic c.98G>A p.(Cys33Tyr) heterozygous variant in the

Indexed as

Botulinum ToxinsDeep Brain StimulationDystonic DisordersTorticollisAdultApoptosis Regulatory ProteinsChildDNA-Binding ProteinsFemaleGlobus PallidusHumansYoung AdultApoptosis Regulatory ProteinsBotulinum ToxinsDNA-Binding ProteinsTHAP1 protein, humandeep brain stimulationdystoniamutationnovelTHAP1

Identifiers

PMID37637848
PMCPMC10453957
OpenAlexW4386049642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.