ArticleInternational journal of general medicine2023
The Influence of Patent Foramen Ovale on the Clinical Features of Migraine without Aura: A Cross-Sectional Study.
Article in International journal of general medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Investigating the Patent Foramen Ovale-Migraine Link in Southern Saudi Arabia.Neurosciences (Riyadh, Saudi Arabia) · 2026Observational
- Diffusion tensor image analysis along the perivascular space index and visual analogue scales in female patients with patent foramen ovale and migraine perform better after percutaneous closure.Quantitative imaging in medicine and surgery · 2025Article
- Patent Foramen Ovale Closure in Special Clinical Situations: More Questions Than Answers?Life (Basel, Switzerland) · 2024Review
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8 authors.
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Abstract
Objective: To investigate the influence of patent foramen ovale (PFO) on the clinical features of migraine without aura (MoA). Methods: We consecutively enrolled 390 MoA patients and compared the frequency of headache, episode duration, and the Visual Analogue Scale (VAS), Headache Impact Test 6 (HIT-6), and European Health Interview Survey-Quality of Life 8-item index (EUROHIS-QOL8) scores of patients with and without PFO, those with the mild right-to-left shunt (RLS) and moderate to large RLS, and those with permanent RLS and latent RLS using a nonparametric Mann-Whitney Results: The prevalence of PFO in the 390 MoA patients was 44.4%. Patients with PFO had significantly higher frequency of headaches, VAS scores, HIT-6 scores, and incidence of white matter lesions than those without PFO (all Conclusion: The migraine features in MoA patients could be influenced by PFO, especially in patients with moderate to large shunt, in whom PFO closure improved the symptoms.
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