Evidence map›Paper›PMID 37637401›Full record

ArticleThe Pan African medical journal2023

Newborn screening for sickle cell disease in Butembo and Beni: a pilot experience in a highland region of the Democratic Republic of Congo.

Mupenzi Mumbere, Salomon Batina-Agasa, Naura Apio Uvoya, Emmanuel Tebandite Kasai, Paul Kambale Kombi, Roland Marini Djang'eing'a, Jean-Pierre Alworong'a Opara

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Article in The Pan African medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mupenzi MumbereDepartment of Pediatrics, Faculty of Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.
Salomon Batina-AgasaDepartment of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Naura Apio UvoyaDepartment of Pediatrics, Faculty of Medicine, University of Bunia, Bunia, Democratic Republic of the Congo.
Emmanuel Tebandite KasaiDepartment of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Paul Kambale KombiDepartment of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Roland Marini Djang'eing'aDepartment of Pharmaceutical Sciences, Laboratory of Analytical Chemistry, Faculty of Medicine, University of Liège, Liège, Belgium.
Jean-Pierre Alworong'a OparaDepartment of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: sickle cell disease is an inherited autosomal recessive hemoglobin disorder resulting in acute and chronic systemic complications. Despite the high burden of sickle cell disease in the Democratic Republic of the Congo, limited data on disease prevalence is available and systematic screening is not offered to newborns. This study aimed to provide neonatal prevalence and associated factors to the phenotypic manifestation of sickle cell disease in an eastern region of the Democratic Republic of the Congo. Methods: the study was conducted from 20 Conclusion: sickle cell disease prevalence is lower in Butembo and Beni than in other regions of the Democratic Republic of the Congo. However, it remains an alarming public health issue. Systematic newborn screening, parent/patient education and early management programs constitute an urgent need to be addressed by decision-makers.

Indexed as

Anemia, Sickle CellAnkle InjuriesDemocratic Republic of the CongoHemoglobin, SickleHumansInfant, NewbornNeonatal ScreeningHemoglobin, SickleBeniButemboDemocratic Republic of the CongoNewborn screeningsickle cell disease

Identifiers

PMID37637401
PMCPMC10460112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.