Evidence map›Paper›PMID 37637356›Full record

ArticleCritical care explorations2023

Epoprostenol Exposure During Pregnancy.

Emily E Naoum, Carolyn LaVita, Natasha Lopez, Alexa Nardone, Marti D Soffer, Kenneth T Shelton

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Management of Pulmonary Hypertension in Pregnancy.Current heart failure reports · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emily E NaoumDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA.
Carolyn LaVitaDepartment of Respiratory Therapy, Massachusetts General Hospital, Boston, MA.
Natasha LopezDepartment of Pharmacy, Massachusetts General Hospital, Boston, MA.
Alexa NardoneDepartment of Pharmacy, Massachusetts General Hospital, Boston, MA.
Marti D SofferDepartment of Obstetrics, Gynecology, and Reproductive Biology, Division of Maternal Fetal Medicine, Massachusetts General Hospital, Boston, MA.
Kenneth T SheltonDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA.
Massachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Institutional policies restricting pregnant providers from caring for patients receiving inhaled epoprostenol exist across the nation based on little to no data to substantiate this practice. Over the last 2 decades, the use of inhaled pulmonary vasodilators has expanded in patients with cardiac and respiratory disease providing more evidence for the safety of these medications in obstetrical patients. We propose a thoughtful consideration and review of the literature to remove this restriction to reduce the need to reveal early pregnancy status to employers, to alleviate undue stress for pregnant caregivers who are exposed to patients receiving epoprostenol, and to ensure safe, equal employment, and learning opportunities for pregnant providers.

Indexed as

acute respiratory distress syndromecardiac critical carecritical carematernal critical careobstetric critical carepulmonary vasodilators

Identifiers

PMID37637356
PMCPMC10456979
OpenAlexW4379467917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.