Evidence map›Paper›PMID 37636890›Full record

ArticleClinical case reports2023

The natural history of Pelizaeus-Merzbacher disease caused by PLP1 duplication: A multiyear case series.

Angela M Trepanier, Sienna Aguilar, John Kamholz, Jeremy J Laukka

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Angela M TrepanierCenter for Molecular Medicine and Genetics Wayne State University School of Medicine Detroit Michigan USA.
Sienna AguilarCenter for Molecular Medicine and Genetics Wayne State University School of Medicine Detroit Michigan USA.
John KamholzCenter for Molecular Medicine and Genetics Wayne State University School of Medicine Detroit Michigan USA.
Jeremy J LaukkaDepartment of Medical Education University of Toledo College of Medicine & Life Sciences Toledo Ohio USA.ORCID https://orcid.org/0009-0006-3855-2160
Wayne State University · USUniversity of Iowa · USUniversity of Toledo Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to characterize the clinical features, developmental milestones, and the natural history of Pelizaeus-Merzbacher disease (PMD) associated with

Indexed as

gene duplicationhumansmutationmyelin proteolipid proteinPelizaeus–Merzbacher disease/geneticsPelizaeus–Merzbacher disease/pathophysiologyphenotype

Identifiers

PMID37636890
PMCPMC10457477
OpenAlexW4386190991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.