Evidence map›Paper›PMID 37636839›Full record

ArticleWellcome open research2022

A network of empirical ethics teams embedded in research programmes across multiple sites: opportunities and challenges in contributing to COVID-19 research and responses.

Nothando Ngwenya, Jennifer Ilo Van Nuil, Deborah Nyirenda, Mary Chambers, Phaik Yeong Cheah, Janet Seeley, Primus Chi, Lindiwe Mafuleka, Busisiwe Nkosi, Dorcas Kamuya and 9 more

Abstract read
In one paragraph

Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Bioethics and the value of disagreement.Journal of medical ethics · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nothando NgwenyaAfrica Health Research Institute, Durban, South Africa.
Jennifer Ilo Van NuilOxford University Clinical Research Unit, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0002-5167-5505
Deborah NyirendaMalawi-Liverpool-Wellcome Clinical Research Programme, Blantyre, Malawi.ORCID https://orcid.org/0000-0002-5867-4687
Mary ChambersOxford University Clinical Research Unit, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0003-0535-3895
Phaik Yeong CheahNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-6327-3266
Janet SeeleyAfrica Health Research Institute, Durban, South Africa.ORCID https://orcid.org/0000-0002-0583-5272
Primus ChiKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID https://orcid.org/0000-0002-2727-2693
Lindiwe MafulekaMalawi-Liverpool-Wellcome Clinical Research Programme, Blantyre, Malawi.
Busisiwe NkosiAfrica Health Research Institute, Durban, South Africa.
Dorcas KamuyaKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID https://orcid.org/0000-0001-7107-1736
Alun DaviesNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-7784-9000
Mira L SchneidersNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-4149-3484
Noni MumbaKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.ORCID https://orcid.org/0000-0002-3531-8823
Siphephelo DlaminiAfrica Health Research Institute, Durban, South Africa.
Nicola DesmondMalawi-Liverpool-Wellcome Clinical Research Programme, Blantyre, Malawi.ORCID https://orcid.org/0000-0002-2874-8569
Vicki MarshNuffield Department of Medicine, University of Oxford, Oxford, UK.
Dinnah RipponEthox, University of Oxford, Oxford, UK.
Michael ParkerEthox, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-7054-4711
Sassy MolyneuxNuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0001-9522-416X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Covid-19 continues to teach the global community important lessons about preparedness for research and effective action to respond to emerging health threats. We share the COVID-19 experiences of a pre-existing cross-site ethics network-the Global Health Bioethics Network-which brings together researchers and practitioners from Africa, Europe, and Southeast Asia. We describe the network and its members and activities, and the work-related opportunities and challenges we faced over a one-year period during the pandemic. We highlight the value of having strong and long-term empirical ethics networks embedded across diverse research institutions to be able to: 1) identify and share relevant ethics challenges and research questions and ways of 'doing research'; 2) work with key stakeholders to identify appropriate ways to contribute to the emerging health issue response - e.g., through ethics oversight, community engagement, and advisory roles at different levels; and 3) learn from each other and from diverse contexts to advocate for positive change at multiple levels. It is our view that being embedded and long term offers opportunities in terms of deep institutional and contextual knowledge, existing relationships and access to a wide range of stakeholders. Being networked offers opportunities to draw upon a wide range of expertise and perspectives, and to bring together internal and external insights (i.e.drawing on different positionalities). Long term funding means that the people and resources are in place and ready to respond in a timely way. However, many tensions and challenges remain, including difficulties in negotiating power and politics in the roles that researchers and research institutions can and should play in an emergency, and the position of empirical ethics within research programmes. We discuss some of these tensions and challenges and consider the implications for our own and similar networks in future.

Indexed as

COVID-19embedded researchethicshealth researchLow and Middle Income Countriesnetwork

Identifiers

PMID37636839
PMCPMC10457565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.