Evidence map›Paper›PMID 37636486›Full record

ArticleTransplantation direct2023

Sex and Gender Disparities in Living Kidney Donation: A Scoping Review.

Eswari Vilayur, Anita van Zwieten, Mingxing Chen, Anna Francis, Melanie Wyld, Siah Kim, Tess Cooper, Germaine Wong

Open access · goldAbstract readScoping Review
In one paragraph

Article in Transplantation direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Gender Differences in Willingness to Be Evaluated for Living Kidney Donation.Progress in transplantation (Aliso Viejo, Calif.) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sex and Gender Disparities in Kidney Transplantation.Advances in kidney disease and health · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Understanding the dynamics of deceased organ donation and utilization in Colombia.Revista panamericana de salud publica = Pan American journal of public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eswari VilayurJohn Hunter Hospital, Hunter New England Health Service, New Lambton, NSW, Australia.
Anita van ZwietenSydney School of Public Health, The University of Sydney, Camperdown, NSW, Australia.
Mingxing ChenCentre for Kidney and Transplantation Research, Westmead Hospital, Westmead, NSW, Australia.
Anna FrancisDepartment of Nephrology, Queensland Children's Hospital, Brisbane, QLD, Australia.
Melanie WyldSydney School of Public Health, The University of Sydney, Camperdown, NSW, Australia.
Siah KimSydney School of Public Health, The University of Sydney, Camperdown, NSW, Australia.
Tess CooperSydney School of Public Health, The University of Sydney, Camperdown, NSW, Australia.
Germaine WongSydney School of Public Health, The University of Sydney, Camperdown, NSW, Australia.
University of Sydney · AUQueensland Children’s Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Women are more likely than men to be living kidney donors. We summarized the evidence concerning the reasons behind sex and gender disparities in living kidney donation (LKD). Methods: A scoping review of quantitative and qualitative evidence on reasons for sex and gender disparities in LKD was conducted from inception to March 2023. Results: Of 1123 studies screened, 45 were eligible for inclusion. Most studies were from North America, Europe, and Central Asia (n = 33, 73%). A predominance of women as living donors (55%-65%) was observed in 15 out of 18 (83%) studies. Reasons for sex and gender disparities in LKD included socioeconomic, biological, and cognitive or emotional factors. A gendered division of roles within the families was observed in most studies, with men being the primary income earner and women being the main caregiver. Fear of loss of income was a barrier to male donation. Human leukocyte antigen sensitization through pregnancy in female recipients precluded male partner donation, whereas female donation was supported by altruism and a positive attitude toward LKD. Conclusions: Sex imbalance in LKD is prevalent, with a predominance of women as living donors. Such disparities are driven by societal and cultural perceptions of gender roles, pregnancy-induced sensitization, and attitudes toward donation and at least some of these factors are modifiable. Donor compensation to support predonation assessments and income loss, implementation of innovative desensitization treatments, promotion of paired kidney exchange program, and targeted educational initiatives to promote equitable living donation may help to close the gender gap in LKD.

Identifiers

PMID37636486
PMCPMC10455160
OpenAlexW4386126222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.