ReviewFrontiers in cardiovascular medicine2023
Physiological reactivity to acute mental stress in essential hypertension-a systematic review.
Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- A dangerous combination: how co-occurring floods and blackouts increase cardiovascular hospitalizations.Journal of exposure science & environmental epidemiology · 2026Article
- Association Between Systolic Blood Pressure at Emergency Department Arrival and Time to Bleeding Cessation in Adult Non-Traumatic Epistaxis: A Retrospective Time-to-Event Analysis.Journal of clinical medicine · 2026Article
- Psychological Burden in Uncontrolled Hypertension: Findings from the ERIDANO Multicenter Study.Journal of clinical medicine · 2026Article
- Economic vulnerability or social inequality? A global comparative analysis of their relative impact on chronic kidney disease burden.Frontiers in public health · 2026Article
- Stress, Anxiety, and Self-Efficacy in Hypertension: Evidence from a Romanian Case-Control Study.Diseases (Basel, Switzerland) · 2025Article
- Acute Physical Exercise Reduces Mental Stress-Induced Responses in Teachers.International journal of environmental research and public health · 2025Article
- Digital Toxicology Teleconsultation for Adult Poisoning Cases in Saudi Hospitals: A Nationwide Study.Healthcare (Basel, Switzerland) · 2025Article
- Identity change and the transition to university: Implications for cortisol awakening response, psychological well-being and academic performance.Applied psychology. Health and well-being · 2025Article
- Article
- The relevance of outcome expectations in group hypnosis for stress reduction: a secondary analysis of a multicenter randomized controlled trial.Frontiers in psychology · 2024Article
- Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam.International journal of ophthalmology · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Exaggerated physiological reactions to acute mental stress (AMS) are associated with hypertension (development) and have been proposed to play an important role in mediating the cardiovascular disease risk with hypertension. A variety of studies compared physiological reactivity to AMS between essential hypertensive (HT) and normotensive (NT) individuals. However, a systematic review of studies across stress-reactive physiological systems including intermediate biological risk factors for cardiovascular diseases is lacking. Methods: We conducted a systematic literature search (PubMed) for original articles and short reports, published in English language in peer-reviewed journals in November and December 2022. We targeted studies comparing the reactivity between essential HT and NT to AMS in terms of cognitive tasks, public speaking tasks, or the combination of both, in at least one of the predefined stress-reactive physiological systems. Results: We included a total of 58 publications. The majority of studies investigated physiological reactivity to mental stressors of mild or moderate intensity. Whereas HT seem to exhibit increased reactivity in response to mild or moderate AMS only under certain conditions (i.e., in response to mild mental stressors with specific characteristics, in an early hyperkinetic stage of HT, or with respect to certain stress systems), increased physiological reactivity in HT as compared to NT to AMS of strong intensity was observed across all investigated stress-reactive physiological systems. Conclusion: Overall, this systematic review supports the proposed and expected generalized physiological hyperreactivity to AMS with essential hypertension, in particular to strong mental stress. Moreover, we discuss potential underlying mechanisms and highlight open questions for future research of importance for the comprehensive understanding of the observed hyperreactivity to AMS in essential hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.