Evidence map›Paper›PMID 37636296›Full record

ArticleFrontiers in cardiovascular medicine2023

Impact of myocardial deformation on risk prediction in patients following acute myocardial infarction.

Torben Lange, Roman J Gertz, Alexander Schulz, Sören J Backhaus, Ruben Evertz, Johannes T Kowallick, Gerd Hasenfuß, Steffen Desch, Holger Thiele, Thomas Stiermaier and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02158468 (Effect of Conditioning on Myocardial Damage in ST-elevation Myocardial Infarction - Comparison of Combined Intrahospital Preconditioning Plus Postconditioning Versus Postconditioning Versus Control.), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02158468 nacompletednot on this map

Effect of Conditioning on Myocardial Damage in ST-elevation Myocardial Infarction - Comparison of Combined Intrahospital Preconditioning Plus Postconditioning Versus Postconditioning Versus Control.

TypeinterventionalSponsorUniversity of LeipzigRan2011 to 2014Enrolled600ConditionsST-elevation Myocardial InfarctionArmsCombined intrahospital pre- and postconditioning, Postconditioning
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  3. Review
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  5. Article
  6. Increased [Basic research in cardiology · 2024
    Article
  7. CMR-based cardiac phenotyping in different forms of heart failure.The international journal of cardiovascular imaging · 2024
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Torben LangeDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Roman J GertzInstitute for Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Alexander SchulzDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Sören J BackhausDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Ruben EvertzDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Johannes T KowallickGerman Center for Cardiovascular Research (DZHK), Partner site Göttingen, Göttingen, Germany.
Gerd HasenfußDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
Steffen DeschDepartment of Internal Medicine/Cardiology and Leipzig Heart Science, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Holger ThieleDepartment of Internal Medicine/Cardiology and Leipzig Heart Science, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Thomas StiermaierMedical Clinic II (Cardiology/Angiology/Intensive Care Medicine), University Heart Center Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany.
Ingo EitelMedical Clinic II (Cardiology/Angiology/Intensive Care Medicine), University Heart Center Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany.
Andreas SchusterDepartment of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany.
German Centre for Cardiovascular Research · DELeipzig Heart Institute · DEUniversity of Göttingen · DEKing's College London · GBUniversitätsmedizin Göttingen · DEUniversity of Cologne · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Strain analyses derived from cardiovascular magnetic resonance-feature tracking (CMR-FT) provide incremental prognostic benefit in patients sufferring from acute myocardial infarction (AMI). This study aims to evaluate and revalidate previously reported prognostic implications of comprehensive strain analyses in a large independent cohort of patients with ST-elevation myocardial infarction (STEMI). Methods: Overall, 566 STEMI patients enrolled in the CONDITIONING-LIPSIA trial including pre- and/or postconditioning treatment in addition to conventional percutaneous coronary intervention underwent CMR imaging in median 3 days after primary percutaneous coronary intervention. CMR-based left atrial (LA) reservoir (Es), conduit (Ee), and boosterpump (Ea) strain analyses, as well as left ventricular (LV) global longitudinal strain (GLS), circumferential strain (GCS), and radial strain (GRS) analyses were carried out. Previously identified cutoff values were revalidated for risk stratification. Major adverse cardiac events (MACE) comprising death, reinfarction, and new congestive heart failure were assessed within 12 months after the occurrence of the index event. Results: Both atrial and ventricular strain values were significantly reduced in patients with MACE ( Conclusion: External validation of CMR-FT-derived LA and LV strain evaluations confirmed the prognostic value of cardiac deformation assessment in STEMI patients. In the present study, LA strain parameters especially enabled further risk stratification and prognostic assessment over and above clinically established risk parameters. Clinical Trial Registration: ClinicalTrials.gov, identifier NCT02158468.

Indexed as

acute myocardial infarct (AMI)cardiovascular magnetic resonancemyocardial feature trackingrisk predictionstrain analyses

Identifiers

PMID37636296
PMCPMC10449121
OpenAlexW4385725345

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.