Evidence map›Paper›PMID 37636186›Full record

ArticleJournal of family medicine and primary care2023

Biomarkers and their combination in a prediction of decompensation after an index hospitalization for acute heart failure.

Azra Durak-Nalbantic, Edin Begic, Alden Begic, Alen Dzubur, Orhan Lepara, Rusmir Baljic, Aida Hamzic-Mehmedbasic, Damir Rebic, Enisa Hodzic, Mirza Halimic and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of family medicine and primary care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Accuracy of analytically determined fractional flow reserve derived from coronary angiography for non-invasive assessment of coronary artery stenosis.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Azra Durak-NalbanticClinic for Heart and Vessel Disease and Rheumatism, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Edin BegicMedical School, Sarajevo School of Science and Tecnology, Hrasnička Cesta 3a, Sarajevo, Bosnia and Herzegovina.
Alden BegicClinic for Heart and Vessel Disease and Rheumatism, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Alen DzuburClinic for Heart and Vessel Disease and Rheumatism, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Orhan LeparaMedical Faculty, University of Sarajevo, Cekalusa 90, Sarajevo, Bosnia and Herzegovina.
Rusmir BaljicClinic for Infective Disease, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Aida Hamzic-MehmedbasicMedical School, Sarajevo School of Science and Tecnology, Hrasnička Cesta 3a, Sarajevo, Bosnia and Herzegovina.
Damir RebicClinic for Nephrology, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Enisa HodzicClinic for Heart and Vessel Disease and Rheumatism, Clinical Center University of Sarajevo, Bolnicka 25, Sarajevo, Bosnia and Herzegovina.
Mirza HalimicPediatric Clinic, Clinical Center University of Sarajevo, Patriotske Lige, 87, Sarajevo, Bosnia and Herzegovina.
Almir BadnjevicInternational Burch University, Faculty of Engineering and Natural Sciences, Genetics and Bioengineering Department, Sarajevo, Bosnia and Herzegovina.
University of Sarajevo · BASarajevo School of Science and Technology · BAClinical Center University of Sarajevo · BAInternational Burch University · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Heart failure (HF) still remains as one of the most common causes of hospital admission with a high mortality rate. Aim: To investigate the possible prognostic role of brain natriuretic peptide (BNP), high-sensitivity (hs) cardiac troponin (cTn) I, cystatin C, and cancer antigen 125 (CA125) in the prediction of decompensation after an index hospitalization and to investigate their possible additive prognostic value. Patients and Methods: Two hundred twenty-two patients hospitalized with acute HF were monitored and followed for 18 months. Results: BNP at discharge has the highest sensitivity and specificity in the prediction of decompensation. For a cutoff value of 423.3 pg/ml, sensitivity was 64.3% and specificity was 64.5%, with a positive predictive value of 71.6% and an area under the curve (AUC) of 0.69 ( Conclusion: BNP, cystatin C, and CA125 are predictors of decompensation, and their combined usage leads to better prediction of new decompensation.

Indexed as

Biomarkersheart failureprediction

Identifiers

PMID37636186
PMCPMC10451570
OpenAlexW4383172242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.