ArticleF1000Research2023
The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescence.
Walaa Alshafie, Maryam Fotouhi, Riham Ayoubi, Irina Shlaifer, Kathleen Southern, Peter S McPherson, Carl Laflamme, NeuroSGC/YCharOS/EDDU collaborative group
Open access · goldAbstract read
In one paragraphArticle in F1000Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors at 1 institution in 1 country.
Walaa AlshafieDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.
Maryam FotouhiDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.
Riham AyoubiDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.
Irina ShlaiferThe Neuro's Early Drug Discovery Unit (EDDU), Structural Genomics Consortium, McGill University, Montreal, Québec, H3A 2B4, Canada.
Kathleen SouthernDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.ORCID 0000-0002-4125-3608 Peter S McPhersonDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.
Carl LaflammeDepartment of Neurology and Neurosurgery, Structural Genomics Consortium, The Montreal Neurological Institute, McGill University, Montreal, Québec, H3A 2B4, Canada.ORCID 0000-0001-5906-025X NeuroSGC/YCharOS/EDDU collaborative group
Montreal Neurological Institute and Hospital · CA
Funding
Motor Neurone Disease Association SGC/JAN18/988-797
6 · The paper itselfAbstract
Charged multivesicular body protein 2B is a subunit of the endosomal sorting complex required for transport III (ESRCT-III), a complex implicated in the lysosomal degradation pathway and formation of multivesicular bodies. Mutations to the
Indexed as
Amyotrophic Lateral SclerosisFrontotemporal DementiaAntibodiesBlotting, WesternFluorescent Antibody TechniqueHumansImmunoprecipitationMultivesicular BodiesReproducibility of ResultsAntibodiesantibody characterizationantibody validationCharged multivesicular body protein 2bCHMP2BimmunofluorescenceimmunoprecipitationUniprot ID Q9UQN3Western Blot
Identifiers
PMID37635943
PMCPMC10448144
OpenAlexW4385237942
What OpenQuestion holds
Textmetadata
LicenceCC BY
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