Evidence map›Paper›PMID 37635854›Full record

ArticleCurrent developmental disorders reports2023

Sex Differences in the Developmental Trajectories of Autism Spectrum Disorder.

Tyler C McFayden, Orla Putnam, Rebecca Grzadzinski, Clare Harrop

Abstract read
In one paragraph

Article in Current developmental disorders reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Sex-specific metrics for success: Gaps in social word use are bigger for autistic girls than boys.Autism : the international journal of research and practice · 2026
    Article
  6. Article
  7. Sex Differences in Autistic Youth Born Extremely Preterm.Journal of autism and developmental disorders · 2026
    Article
  8. Article
  9. Article
  10. Reports of Echolalia and Related Behaviors in Autism From Parents, Teachers, and Clinicians: Evidence From the Simon Simplex Collection.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Are the diagnostic rates of autistic females increasing? An examination of state-wide trends.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tyler C McFaydenCarolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, USA.ORCID 0000-0001-8942-1562
Orla PutnamDepartment of Allied Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, USA.ORCID 0000-0002-2215-0021
Rebecca GrzadzinskiCarolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, USA.ORCID 0000-0001-7764-6166
Clare HarropDepartment of Allied Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, USA.ORCID 0000-0003-3381-3473

Funding

North Carolina Translational and Clinical Science Institute (NC TraCS) KL2KL2TR002490 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2018 to 2022
$11.0M
Postdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5M
NCATS NIH HHS KL2 TR002490NICHD NIH HHS T32 HD040127
6 · The paper itself

Abstract

Purpose of Review: Females and males are disproportionately diagnosed with autism, a sex difference that has historically represented this neurodevelopmental condition. The current review examines lifespan developmental trajectories of autism based on sex to elucidate behavioral phenotypic differences that may contribute to differential rates of diagnosis. Recent Findings: We review sex differences in diagnostic criteria: social communication and restricted interests/repetitive behaviors (RRBs). Results suggest RRBs are more indicative of a diagnosis in males, whereas social differences are more indicative of a diagnosis in females. Factors contributing to a later diagnosis in females include social strengths (camouflaging) and diagnostic overshadowing. Summary: Sex differences in diagnostic criteria may contribute to differential rates of identification in males and females. Sex differences are most pronounced when assessing naturalistic social communication instead of reliance on standardized measure. Numerous future directions are identified including increasing samples of sub-threshold autistic females and evaluating longitudinal sex differences.

Indexed as

AutismCo-occurring conditionsRestricted interests/repetitive behaviorsSex/genderSocial communication

Identifiers

PMID37635854
PMCPMC10457022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.