ArticleFrontiers in human neuroscience2023
Is transcranial direct current stimulation (tDCS) effective to improve cognition and functionality after severe traumatic brain injury? A perspective article and hypothesis.
Article in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- Effect of Transcranial Direct Current Stimulation on Memory and Emotional Recovery in Patients with Stroke and Traumatic Brain Injury: A Prospective, Multicenter, Interventional Pilot Study.Journal of clinical medicine · 2025Article
- Effectiveness of Transcranial Direct Current Stimulation on Cognitive Function: A Pilot Study.Medical journal of the Islamic Republic of Iran · 2025Article
- The awakening effect of hyperbaric oxygen therapy combined with systematic auditory stimulation in comatose patients with craniocerebral injury and its influence on serum biomarkers.Frontiers in neurologyArticle
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
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Abstract
Severe traumatic brain injury (sTBI) is an important cause of disability and mortality and affects people of all ages. Current scientific evidence indicates that motor dysfunction and cognitive impairment are the main limiting factors in patients with sTBI. Transcranial direct current stimulation (tDCS) seems to be a good therapeutic option, but when it comes to patients with sTBI, the results are inconclusive, and some protocols have not yet been tested. In addition, there is still a lack of information on tDCS-related physiological mechanisms, especially during the acute phase. In the present study, based on current evidence on tDCS mechanisms of action, we hypothesized that performing tDCS sessions in individuals with sTBI, especially in the acute and subacute phases, together with conventional therapy sessions, could improve cognition and motor function in this population. This hypothesis presents a new possibility for treating sTBI, seeking to elucidate the extent to which early tDCS may affect long-term clinical outcomes.
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