Evidence map›Paper›PMID 37635779›Full record

ArticleMovement disorders clinical practice2023

Distal Upper Limb Tremor during Walking in Parkinson's Disease.

Matteo Costanzo, Carolina Cutrona, Giorgio Leodori, Maria Ilenia De Bartolo, Andrea Fabbrini, Giorgio Vivacqua, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Daniele Belvisi

Open access · hybridAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Matteo CostanzoIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0002-4369-014X
Carolina CutronaIRCCS Neuromed Pozzilli Italy.
Giorgio LeodoriIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0002-6631-6740
Maria Ilenia De BartoloIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0002-8747-9805
Andrea FabbriniDepartment of Human Neurosciences Sapienza University of Rome Rome Italy.
Giorgio VivacquaDepartment of Experimental Morphology and Microscopy - Integrated Research Center (PRAAB) - Campus Biomedico University of Rome Rome Italy.ORCID https://orcid.org/0000-0001-6080-7007
Antonella ConteIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0002-6338-2961
Giovanni FabbriniIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0001-7614-8771
Alfredo BerardelliIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0003-3598-3142
Daniele BelvisiIRCCS Neuromed Pozzilli Italy.ORCID https://orcid.org/0000-0001-8681-3050
Istituto Neurologico Mediterraneo · ITSapienza University of Rome · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Distal upper limb tremor during walking (TW) is frequently observed in Parkinson's disease (PD) but its clinical features are unknown. Objective: To characterize the occurrence and the clinical features of TW in comparison to the other types of tremors in PD. Methods: Fifty-one PD patients with rest tremor were evaluated off- and on-treatment. Occurrence, body distribution, severity and latency of TW and of other tremor types were assessed. Results: TW was present in 78% of the PD patients examined. TW body distribution and severity were similar to those of rest and re-emergent tremor but different from the postural tremor presented by the same patients. TW latency, observed in 85% of patients, was on average 5.8 s. Dopaminergic treatment significantly improved TW, rest, and re-emergent tremor severity but left TW latency unaffected. Conclusions: TW is a frequent motor sign in PD and is likely a clinical variant of rest tremor.

Indexed as

gaitneurodegenerative diseaseParkinson's diseasetremortremor during walking

Identifiers

PMID37635779
PMCPMC10450241
OpenAlexW4380482167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.