Evidence map›Paper›PMID 37635750›Full record

ArticleFrontiers in synaptic neuroscience2023

Synaptic alterations and neuronal firing in human epileptic neocortical excitatory networks.

Réka Bod, Kinga Tóth, Nour Essam, Estilla Zsófia Tóth, Loránd Erõss, László Entz, Attila G Bagó, Dániel Fabó, István Ulbert, Lucia Wittner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Fully Automated Azeotropic Drying-Free Synthesis of [Molecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Virtual brain twins for stimulation in epilepsy.Nature computational science · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Réka Bod *Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Kinga Tóth *Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Nour EssamInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Estilla Zsófia TóthInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Loránd ErõssNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
László EntzNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
Attila G BagóNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
Dániel FabóNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
István UlbertInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Lucia WittnerInstitute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
HUN-REN Research Centre for Natural Sciences · HUSemmelweis University · HUInstitute of Cognitive Neuroscience and Psychology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is a prevalent neurological condition, with underlying neuronal mechanisms involving hyperexcitability and hypersynchrony. Imbalance between excitatory and inhibitory circuits, as well as histological reorganization are relatively well-documented in animal models or even in the human hippocampus, but less is known about human neocortical epileptic activity. Our knowledge about changes in the excitatory signaling is especially scarce, compared to that about the inhibitory cell population. This study investigated the firing properties of single neurons in the human neocortex

Indexed as

epilepsyexcitatory systemhuman neocortexsingle unit activitysynaptic reorganizationsynchronous population activity

Identifiers

PMID37635750
PMCPMC10450510
OpenAlexW4385738642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.