Evidence map›Paper›PMID 37635195›Full record

Trial reportScientific reports2023

Microsurgical robotic system enables the performance of microvascular anastomoses: a randomized in vivo preclinical trial.

Gerardo Malzone, Giulio Menichini, Marco Innocenti, Alberto Ballestín

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. In vivo microsurgical training with the symaniJournal of robotic surgery · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Dual robotic surgery: Da Vinci SPJournal of robotic surgery · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gerardo MalzoneDivision of Plastic, Reconstructive and Microsurgery, CTO Careggi University Hospital, Florence, Tuscany, Italy.
Giulio MenichiniDivision of Plastic, Reconstructive and Microsurgery, CTO Careggi University Hospital, Florence, Tuscany, Italy.
Marco InnocentiDivision of Plastic, Reconstructive and Microsurgery, CTO Careggi University Hospital, Florence, Tuscany, Italy.
Alberto BallestínTumor Microenvironment Laboratory, Institut Curie, Orsay - Paris, France. balles_rodriguez@hotmail.com.ORCID http://orcid.org/0000-0002-7150-9758

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Technical advances in microsurgery have enabled complex oncological reconstructions by performing free tissue transfers, nerve and lymphatic reconstructions. However, the manual abilities required to perform microsurgery can be affected by human fatigue and physiological tremor resulting in tissue damage and compromised outcomes. Robotic assistance has the potential to overcome issues of manual microsurgery by improving clinical value and anastomoses' outcomes. The Symani Surgical System, a robotic platform designed for microsurgery, was used in this in-vivo preclinical study using a rat animal model. The tests included anastomoses on veins and arteries performed by microsurgeons manually and robotically, with the latter approach using Symani. The anastomoses were assessed for patency, histopathology, and execution time. Patency results confirmed that the robotic and manual techniques for venous and arterial anastomoses were equivalent after anastomosis, however, the time to perform the anastomosis was longer with the use of the robot (p < 0.0001). Histological analysis showed less total average host reaction score at the anastomotic site in robotic anastomosis for both veins and arteries. This study demonstrates the equivalence of vessel patency after microsurgical anastomoses with the robotic system and with manual technique. Furthermore, robotic anastomosis has proven to be slightly superior to manual anastomosis in terms of decreased tissue damage, as shown by histological analysis.

Indexed as

Essential TremorRobotic Surgical ProceduresAnastomosis, SurgicalAnimalsArteriesHumansRatsVeins

Identifiers

PMID37635195
PMCPMC10460789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.