Evidence map›Paper›PMID 37634970›Full record

ArticleJournal of the National Medical Association2023

Black Americans have worse stroke outcome compared with non-Hispanic whites.

Lewis B Morgenstern, Mellanie V Springer, Neil C Porter, Madeline Kwicklis, Joseph F Carrera, Cemal B Sozener, Morgan S Campbell, Imadeddin Hijazi, Lynda D Lisabeth

Abstract read
In one paragraph

Article in Journal of the National Medical Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Racial and Ethnic Disparities in Stroke Incidence and Outcomes.Current cardiovascular risk reports · 2025
    Article
  6. The Color of Medicine.Annals of family medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lewis B MorgensternDepartment of Neurology, University of Michigan Medical School, Ann Arbor; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor; Department of Emergency Medicine, University of Michigan Medical School, Ann Arbor. Electronic address: lmorgens@umich.edu.
Mellanie V SpringerDepartment of Neurology, University of Michigan Medical School, Ann Arbor.
Neil C PorterDepartment of Neurology, University of Maryland, Baltimore.
Madeline KwicklisDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor.
Joseph F CarreraDepartment of Neurology, University of Michigan Medical School, Ann Arbor.
Cemal B SozenerDepartment of Emergency Medicine, University of Michigan Medical School, Ann Arbor.
Morgan S CampbellCHRISTUS Spohn Hospitals, CHRISTUS Health system, Corpus Christi, Texas.
Imadeddin HijaziDepartment of Neurology, University of Michigan Medical School, Ann Arbor.
Lynda D LisabethDepartment of Neurology, University of Michigan Medical School, Ann Arbor; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor.

Funding

STROKE SURVEILLANCE IN A BIETHNIC COMMUNITYR01NS038916 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LISABETH, LYNDA D, MORGENSTERN, LEWIS B · 1999 to 2023
$20.9M
Partnering with an Urban Safety Net Hospital to Deliver Stroke Preparedness in the Emergency DepartmentK01NS117555 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SPRINGER, MELLANIE V · 2020 to 2024
$1.2M
NINDS NIH HHS K01 NS117555NINDS NIH HHS R01 NS038916
6 · The paper itself

Abstract

introductionWe studied racial differences in post-stroke outcomes using a prospective, population-based cohort of stroke survivors as part of the Brain Attack Surveillance in Corpus Christi (BASIC) project.

methodsNeurologic (NIHSS, range of 0-42, higher scores are worse), functional (ADLs/IADLs, range 1-4, higher scores are worse), and cognitive (3MSE, range 0-100, higher scores are better) outcomes were measured 90 days after stroke. Cox proportional hazards and negative binomial linear regression models were used to examine the associations between race and 90-day all-cause mortality and NIHSS, respectively, whereas linear regression was used for ADLs/IADLs and 3MSE scores. Covariates included demographics, initial NIHSS, comorbidities, prior stroke history, tPA treatment status, pre-stroke disability, and pre-stroke cognition. The mortality model was also adjusted for DNR status.

resultsAt 90 days post-stroke, Black American individuals (BAs) (n = 122) had a median (IQR) NIHSS of 2 (1,6) compared to NIHSS of 1 (0,3) in non-Hispanic White American individuals (NHWs) (n = 795). BAs had a median (IQR) ADL/IADL score of 2.41 (1.50, 3.39) compared to 2.00 (1.27, 2.95) in NHWs. BAs scored a median of 84 (75, 92) on the 3MSE compared to NHWs' score of 91.5 (83, 96). Death occurred in 23 (8%) of BAs and 268 (15%) of NHWs within 90 days among those who participated in baseline. After adjustment for covariates, functional outcomes at 90 days were worse in BAs compared to NHWs, with 15.8% (95% CI=5.2, 26.4) greater limitations in ADLs/IADLs and 43.9% (95% CI=12.0, 84.9) greater severity of stroke symptoms. Cognition at 90 days was 6.5% (95% CI=2.4, 10.6) lower in BAs compared to NHWs. BAs had a 35.4% lower (95% CI=-9.8, 61.9) hazard rate of mortality than NHWs.

conclusionsIn this prospective, population-based community sample, BAs had worse neurologic, functional and cognitive outcomes at 90 days compared to NHWs. Future research should investigate how social determinants of health including structural racism, neighborhood factors and access to preventive and recovery services influences these racial disparities.

Indexed as

StrokeWhiteBlack or African AmericanHumansProspective StudiesRisk FactorsUnited StatesBlack AmericansDisparitiesEpidemiologyHealth EquityOutcomeStroke

Identifiers

PMID37634970
PMCPMC10591825

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.