Evidence map›Paper›PMID 37634136›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023

Autologous minced cartilage repair for chondral and osteochondral lesions of the knee joint demonstrates good postoperative outcomes and low reoperation rates at minimum five-year follow-up.

Armin Runer, Robert Ossendorff, Felix Öttl, Vincent A Stadelmann, Stefan Schneider, Stefan Preiss, Gian M Salzmann, Jakob Hax

Registry-linked trialAbstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07641868 (Management of Focal Cartilage Lesions of the Knee), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07641868 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Management of Focal Cartilage Lesions of the Knee: The Benefits of an Autograft Procedure

TypeinterventionalSponsorLouis Pasteur Santé LorraineRan2026 to 2030Enrolled80ConditionsFocal Cartilage Lesions of the KneeArmsManagement of focal cartilage lesions of the knee: micro-fracture, Minced Cartilage Implantation (MCI)
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Treatment Options for Focal Cartilage Lesions of the Knee.Deutsches Arzteblatt international · 2026
    Review
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  15. COArthroscopy techniques · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Armin RunerDepartment of Sports Orthopaedics, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany. armin.runer@tum.de.ORCID http://orcid.org/0000-0001-9901-6552
Robert OssendorffDepartment for Orthopaedics and Trauma, University Hospital Bonn, Bonn, Germany.
Felix ÖttlDepartment of Hip and Knee Surgery, Schulthess Klinik, Zurich, Switzerland.
Vincent A StadelmannDepartment of Research and Development, Schulthess Klinik, Zurich, Switzerland.
Stefan SchneiderOrthocentrum Hamburg, Hamburg, Germany.
Stefan PreissDepartment of Hip and Knee Surgery, Schulthess Klinik, Zurich, Switzerland.
Gian M SalzmannDepartment of Hip and Knee Surgery, Schulthess Klinik, Zurich, Switzerland.
Jakob HaxDepartment of Hip and Knee Surgery, Schulthess Klinik, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMinced cartilage is a one-step, autologous procedure with promising short-term results. The aim of the present study was to evaluate mid-term results in a patient cohort with chondral and osteochondral lesions in the knee joint treated with minced cartilage.

methodsFrom 2015 through 2016, a total of 34 consecutive patients were treated with a single-step, autologous minced cartilage for knee chondral and osteochondral lesions. Numeric analogue scale (NAS) for pain and knee function were obtained prior to surgery and at 12, 24 and 60 months postoperatively. Secondary outcomes, including Lysholm score, Tegner activity score, and the International Knee Documentation Committee (IKDC) score, were recorded at final follow-up. MRI examinations of patients with unplanned radiological follow-up were analysed using the MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) score.

resultsA total of 28 patients (44.1% females, age at surgery: 29.5 ± 11.5 years) were available at a mean follow-up of 65.5 ± 4.1 months. Mean defect size was 3.5 ± 1.8 cm

conclusionOne-step, autologous minced cartilage repair of chondral and osteochondral lesions of the knee without the necessity for subchondral bone treatment demonstrated good patient-reported outcomes, low complication rates, and graft longevity at mid-term follow-up. Minced cartilage represents a viable treatment option to more traditional cartilage repair techniques even in mid-term. LEVEL OF EVIDENCE: Level III.

Indexed as

Cartilage, ArticularAdolescentAdultFemaleFollow-Up StudiesHumansKnee JointMagnetic Resonance ImagingMalePainReoperationTransplantation, AutologousYoung AdultArticular cartilageArticular cartilage resurfacing, patient-reported outcomesCartilageChondral lesionMinced cartilageParticulated cartilage, knee

Identifiers

PMID37634136
PMCPMC10598129

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.