Evidence map›Paper›PMID 37633902›Full record

ArticleMalaria journal2023

Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi.

Christopher C Stanley, James Chirombo, Harrison Msuku, Vincent S Phiri, Noel Patson, Lawrence N Kazembe, Jobiba Chinkhumba, Atupele Kapito-Tembo, Don P Mathanga

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Christopher C StanleyMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi. cstanley@mac.kuhes.ac.mw.
James ChiromboMalawi-Liverpool-Wellcome Clinical Research Programme, Blantyre, Malawi.
Harrison MsukuMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi.
Vincent S PhiriSchool of Global and Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi.
Noel PatsonMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi.
Lawrence N KazembeDepartment of Computing, Mathematical and Statistical Sciences, University of Namibia, Windhoek, Namibia.
Jobiba ChinkhumbaMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi.
Atupele Kapito-TemboMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi.
Don P MathangaMAC-Communicable Diseases Action Centre, Kamuzu University of Health Sciences, Chichiri, Private Bag 360, Blantyre, Malawi.
Kamuzu Central Hospital · MWKamuzu University of Health SciencesUniversity of Liverpool · GBUniversity of Malawi · MWUniversity of Namibia · NA

Funding

World Health Organization HTMGMP03
6 · The paper itself

Abstract

backgroundIn Malawi, malaria is responsible for 40% of hospital deaths. Prompt diagnosis and effective treatment within 24 h of fever onset is critical to prevent progression from uncomplicated to severe disease and to reduce transmission.

methodsAs part of the large evaluation of the malaria vaccine implementation programme (MVIP), this study analysed survey data to investigate whether prompt treatment-seeking behaviour is clustered at community-level according to socio-economic demographics.

resultsFrom 4563 households included in the survey, 4856 children aged 5-48 months were enrolled. Out of 4732 children with documented gender, 52.2% were female and 47.8% male. Among the 4856 children, 33.8% reported fever in the two weeks prior to the survey. Fever prevalence was high in communities with low socio-economic status (SES) (38.3% [95% CI: 33.7-43.5%]) and low in areas with high SES (29.8% [95% CI: 25.6-34.2%]). Among children with fever, 648 (39.5%) sought treatment promptly i.e., within 24 h from onset of fever symptoms. Children were more likely to be taken for prompt treatment among guardians with secondary education compared to those without formal education (aOR:1.37, 95% CI: 1.11-3.03); in communities with high compared to low SES [aOR: 2.78, 95% CI: 1.27-6.07]. Children were less likely to be taken for prompt treatment if were in communities far beyond 5 km to health facility than within 5 km [aOR: 0.44, 95% CI: 0.21-0.92].

conclusionThe high heterogeneity in prevalence of fever and levels of prompt treatment-seeking behaviour underscore the need to promote community-level malaria control interventions (such as use of long-lasting insecticide-treated nets (LLINs), indoor residual spraying (IRS), intermittent preventive therapy (IPT), presumptive treatment and education). Programmes aimed at improving treatment-seeking behaviour should consider targeting communities with low SES and those far from health facility.

Indexed as

MalariaMalaria VaccinesMalnutritionChildEducational StatusFemaleFeverHumansMalawiMaleMalaria VaccinesFeverMalariaMalawiPrompt treatment-seeking

Identifiers

PMID37633902
PMCPMC10463323
OpenAlexW4386191981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.