ArticleBMC pediatrics2023
Clinical presentations and outcomes of pancreaticobiliary maljunction in different pediatric age groups.
Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Advances in Minimally Invasive Diagnosis and Treatment Procedures for Pancreaticobiliary Maljunction: A Narrative Review.Digestive diseases and sciences · 2026Review
- Clinico-radiological attributes of abnormal pancreaticobiliary junction.Abdominal radiology (New York) · 2025Article
- Pancreaticobiliary Reflux with Normal and Relatively Long Common Channels Causing Cholelithiasis and Acute Pancreatitis in Children.Journal of clinical medicine · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPancreaticobiliary maljunction (PBM) is a congenital defect, with risk of developing various pancreaticobiliary and hepatic complications. The presentations of PBM in children and adults are believed to be different, but studies on PBM children of different age groups are limited. This study was to evaluate clinicopathologic characteristics and outcomes in PBM children of different ages.
methodsA total of 166 pediatric patients with PBM were reviewed retrospectively. Clinicopathological, imaging, laboratory, surgical, and follow-up data were collected and analyzed. The patients were divided into three age groups, namely, group A (< 1 year, n = 31), group B (1-3 years, n = 63), and group C (> 3 years, n = 72).
resultsThe major clinical manifestation was jaundice in group A and abdominal pain and vomiting in groups B and C. Acute pancreatitis was more often seen in group C than group A. The length of common channel was significantly longer in group C than group A, while the maximum diameter of common bile duct in group C was smaller than that in group A. Cholangitis and cholecystitis were more commonly performed in groups B and C, while hepatic fibrosis in group A. Whether preoperatively or postoperatively, group C was more likely to have elevated serum amylase, while groups A and B were more likely to present with abnormal liver function indicators, including the increase of aspartate transaminase, alanine transaminase, and gamma-glutamyl transpeptidase.
conclusionPresentation of PBM varies among different pediatric age groups, thus suggesting that targeted management should be carried out according to these differences.
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