ArticleRheumatology (Oxford, England)2024
Mortality and causes of death in systemic lupus erythematosus in New Zealand: a population-based study.
Article in Rheumatology (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The vascular endothelial growth factor as a candidate biomarker of systemic lupus erythematosus: a GRADE-assessed systematic review and meta-analysis.Clinical and experimental medicine · 2024Pooled it
- National trends in hospitalisation, in-hospital mortality and resource use for SLE in Spain from 2016 to 2022.Lupus science & medicine · 2026Article
- T-Cell Immunosenescence in Systemic Lupus Erythematosus: Molecular Mechanisms and Therapeutic Perspectives.Clinical reviews in allergy & immunology · 2026Review
- The incidence, mortality and complications of systemic lupus erythematosus: a population-level cohort study from 2012 to 2023.Rheumatology (Oxford, England) · 2026Article
- Systemic lupus erythematosus-related mortality declined but disparities persisted in the United States: a nationwide multiple-cause-of-death analysis, 1999-2023.Frontiers in immunology · 2026Observational
- Clinical, humanistic, and economic burden of systemic lupus erythematosus in the Kingdom of Saudi Arabia.Cost effectiveness and resource allocation : C/E · 2025Review
- Living Young With Lupus: A Case Report on the Challenges of Multi-System Disease in a Young Adult.Cureus · 2025Article
- Trends in chronic kidney disease mortality among patients with systemic lupus erythematosus: a U.S. population-based study (1999-2020).BMC nephrology · 2025Article
- Thromboembolic Episodes in Patients with Systemic Lupus Erythematosus Without Atrial Fibrillation/Atrial Flutter Are Related to the Presence of at Least 3 Points in the CHAJournal of clinical medicine · 2025Article
- Achievement of lupus low disease activity state (LLDAS) in a New Zealand cohort: a prospective study of ethnic differences in outcomes.Rheumatology advances in practice · 2025Article
- Article
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Authors and funding
6 authors.
Funding
Abstract
objectivesThis study aims to assess the mortality of systemic lupus erythematosus (SLE) patients and examine whether there are variations by subgroup.
methodsSLE patients from 2005 to 2021 were identified from the national administrative datasets. The underlying causes of death were examined. Standardized mortality ratio (SMR) was estimated to compare the relative rate of observed deaths in SLE patients with expected deaths in the general population. The hazard ratios (HR) and 95% confidence intervals (CI) of all-cause mortality and SLE specific mortality by ethnicity were estimated after adjustment for age using a Cox proportional hazards model.
resultsOf the 2802 patients included for analysis, 699 (24.9%) died with 209 (29.9%) SLE deaths. The age-standardized mortality rate of SLE was 0.29 per 100 000 for women and 0.05 for men. The mean age at death was 65.3 (17.1) years. Younger patients were more likely to have SLE as the underlying cause of death, from 78.9% for those under 20 years old to 18.7% for those aged 70-79 years. Compared with the general population, SLE patients were four times more likely to die (SMR: 4.0; 95% CI: 3.7, 4.3). Young patients had higher SMRs than older patients. Māori had worse all-cause mortality (HR: 1.72; 95% CI: 1.10, 2.67) and SLE specific mortality (HR: 2.60; 95% CI: 1.29, 5.24) than others.
conclusionsThe outcomes of SLE in New Zealand were still very poor compared with the general population. Māori with SLE had worse survival than others. Further research is needed to identify the reasons for this disparity.
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