Evidence map›Paper›PMID 37632643›Full record

SynthesisTechniques in coloproctology2023

Complete mesocolic excision for right hemicolectomy: an updated systematic review and meta-analysis.

G De Lange, J Davies, C Toso, G Meurette, F Ris, J Meyer

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Techniques in coloproctology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  17. Quality assessment of surgery for colorectal cancer: Where do we stand?World journal of gastrointestinal surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

G De LangeMedical School, University of Geneva, Rue Michel-Servet 1, 1206, Geneva, Switzerland.
J DaviesCambridge Colorectal Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
C TosoMedical School, University of Geneva, Rue Michel-Servet 1, 1206, Geneva, Switzerland.
G MeuretteMedical School, University of Geneva, Rue Michel-Servet 1, 1206, Geneva, Switzerland.
F RisMedical School, University of Geneva, Rue Michel-Servet 1, 1206, Geneva, Switzerland.
J MeyerMedical School, University of Geneva, Rue Michel-Servet 1, 1206, Geneva, Switzerland. jeremy.meyer@hcuge.ch.ORCID 0000-0003-3381-9146
University of Geneva · CHUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeComplete mesocolic excision improves lymphadenectomy for right hemicolectomy and respects the embryological planes. However, its effect on cancer-free and overall survival is questioned. Therefore, we aimed to determine the potential benefits of the technique by performing a systematic review of the literature and meta-analysis of the available evidence.

methodsWeb of Science, PubMed/Medline, and Embase were searched on February 22, 2023. Original studies on short- and long-term oncological outcomes of adult patients undergoing right hemicolectomy with complete mesocolic excision as a treatment for primary colon cancer were considered for inclusion. Outcomes were extracted and pooled using a model with random effects.

resultsA total of 586 publications were identified through database searching, and 18 from citation searching. Exclusion of 552 articles left 24 articles for inclusion. Meta-analysis showed that complete mesocolic excision increased the lymph node harvest (5 studies, 1479 patients, MD 9.62, 95% CI 5.83-13.41, p > 0.0001, I

conclusionMeta-analysis of observational and randomised studies showed that right hemicolectomy with complete mesocolic excision for primary right colon cancer improves oncologic results without increasing morbidity/mortality. These results need to be confirmed by high-quality evidence and randomised trials in selected patients to assess who may benefit from the procedure.

Indexed as

Colonic NeoplasmsLaparoscopyMesocolonAdultColectomyDisease-Free SurvivalHumansLymph Node ExcisionLymph NodesTreatment OutcomeCancerColonComplete mesocolic excisionD3 lymphadenectomySurgery

Identifiers

PMID37632643
PMCPMC10562294
OpenAlexW4386195300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.