Evidence map›Paper›PMID 37632587›Full record

ReviewBiochemical genetics2024

A Review of the Potential Role of CoQ10 in the Treatment of Hepatocellular Carcinoma.

Mahsa Liaghat, Mohammad Yaghoubzad-Maleki, Mohsen Nabi-Afjadi, Zeinab Fathi, Hamidreza Zalpoor, Nafiseh Heidari, Elham Bahreini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Biochemical genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Exploring Plasma Coenzyme QAntioxidants (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Mahsa LiaghatDepartment of Medical Laboratory Sciences, Faculty of Medical Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
Mohammad Yaghoubzad-MalekiDivision of Biochemistry, Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Mohsen Nabi-AfjadiDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Zeinab FathiMedical School, Tehran University of Medical Sciences, Tehran, Iran.
Hamidreza ZalpoorShiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Nafiseh HeidariDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, P.O. Box: 1449614525, Tehran, Iran.
Elham BahreiniDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, P.O. Box: 1449614525, Tehran, Iran. bahreini.e@iums.ac.ir.ORCID http://orcid.org/0000-0001-6823-8638
Iran University of Medical Sciences · IRIslamic Azad University Kazeron · IRShiraz University of Medical Sciences · IRTarbiat Modares University · IRTehran University of Medical Sciences · IRUniversity of Tabriz · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coenzyme ubiquinone-10 (CoQ10) is not only an important part of the electron transport chain of the mitochondrial inner membrane but also has complex biological functions beyond mitochondrial respiration. It is a natural nutrient that is not only produced by the body but is also found in foods, such as meat, eggs, fish, and vegetable oils. Because some types of cancer reduce CoQ10 blood levels, the use of CoQ10 supplements is recommended for the treatment of cancer patients. The anti-cancer effects of CoQ10 supplementation have been reported in several cancers, including colon and breast cancer. CoQ10 scavenges free radicals to reduce oxidative stress and minimize tissue damage. CoQ10 protects the body from damage caused by chemotherapy drugs by reducing the production of inflammatory cytokines and other inflammatory factors. Recent studies suggest that CoQ10 may be a supplement to pharmacotherapy for hepatocellular carcinoma. This article examines the effects of CoQ10 in hepatocellular carcinoma.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsHumansOxidative StressUbiquinonecoenzyme Q10UbiquinoneCoenzyme Q10Hepatocellular carcinomaOxidative stressUbiquinone

Identifiers

PMID37632587
OpenAlexW4386193627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.