Evidence map›Paper›PMID 37632103›Full record

ArticleViruses2023

Deubiquitinase OTUD6A Regulates Innate Immune Response via Targeting UBC13.

Zhiwei Li, Guanwen Li, Yunfei Li, Yujie Luo, Yuhan Jiang, Ziyu Zhang, Ziyi Zhou, Shengde Liu, Chen Wu, Fuping You

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. OTU deubiquitinases in disease: roles and targeting.Trends in molecular medicine · 2026
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhiwei LiCollege of Life Sciences, Hebei University, Baoding 071002, China.
Guanwen LiCollege of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Yunfei LiDepartment of Systems Biomedicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Yujie LuoDepartment of Systems Biomedicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Yuhan JiangCollege of Life Sciences, Hebei University, Baoding 071002, China.
Ziyu ZhangCollege of Life Sciences, Hebei University, Baoding 071002, China.
Ziyi ZhouCollege of Life Sciences, Hebei University, Baoding 071002, China.
Shengde LiuDepartment of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital and Institute, Beijing 100142, China.
Chen WuCollege of Life Sciences, Hebei University, Baoding 071002, China.
Fuping YouDepartment of Systems Biomedicine, Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.ORCID 0000-0002-7444-729X
Hebei University · CNPeking University · CNSouth China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OTUD6A is a deubiquitinase that plays crucial roles in various human diseases. However, the precise regulatory mechanism of OTUD6A remains unclear. In this study, we found that OTUD6A significantly inhibited the production of type I interferon. Consistently, peritoneal macrophages and bone marrow-derived macrophages from

Indexed as

Herpesvirus 1, HumanInterferon Type IAnimalsDeubiquitinating EnzymesHumansImmunity, InnateMacrophagesMiceDeubiquitinating EnzymesInterferon Type IIFNβinnate immunityNF-κBOTUD6AUBC13

Identifiers

PMID37632103
PMCPMC10458163
OpenAlexW4385986562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.