Evidence map›Paper›PMID 37632004›Full record

ArticleViruses2023

Increase in SARS-CoV-2 Seroprevalence in UK Domestic Felids Despite Weak Immunogenicity of Post-Omicron Variants.

Grace B Tyson, Sarah Jones, Chloe Montreuil-Spencer, Nicola Logan, Sam Scott, Hagar Sasvari, Michael McDonald, Leigh Marshall, Pablo R Murcia, Brian J Willett and 2 more

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Grace B TysonMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
Sarah JonesMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.ORCID 0000-0003-0049-7187
Chloe Montreuil-SpencerSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK.
Nicola LoganMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
Sam ScottMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
Hagar SasvariMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
Michael McDonaldSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK.
Leigh MarshallSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK.
Pablo R MurciaMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.ORCID 0000-0002-4352-394X
Brian J WillettMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.ORCID 0000-0001-8912-3266
William WeirSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow G61 1QH, UK.
Margaret J HosieMRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.ORCID 0000-0002-4313-5023

Funding

Biotechnology and Biological Sciences Research Council BB/V019929/1Medical Research Council MC_PC_19026Medical Research Council MC_UU_00034/6
6 · The paper itself

Abstract

Throughout the COVID-19 pandemic, SARS-CoV-2 infections in domestic cats have caused concern for both animal health and the potential for inter-species transmission. Cats are known to be susceptible to the Omicron variant and its descendants, however, the feline immune response to these variants is not well defined. We aimed to estimate the current seroprevalence of SARS-CoV-2 in UK pet cats, as well as characterise the neutralising antibody response to the Omicron (BA.1) variant. A neutralising seroprevalence of 4.4% and an overall seroprevalence of 13.9% was observed. Both purebred and male cats were found to have the highest levels of seroprevalence, as well as cats aged between two and five years. The Omicron variant was found to have a lower immunogenicity in cats than the B.1, Alpha and Delta variants, which reflects previous reports of immune and vaccine evasion in humans. These results further underline the importance of surveillance of SARS-CoV-2 infections in UK cats as the virus continues to evolve.

Indexed as

COVID-19SARS-CoV-2AnimalsCatsChild, PreschoolHumansMalePandemicsSeroepidemiologic StudiesUnited KingdomcatscoronavirusesELISAfeline infectionsneutralising antibodiesSARS-CoV-2serology

Identifiers

PMID37632004
PMCPMC10458763

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.