Evidence map›Paper›PMID 37631912›Full record

ArticleVaccines2023

The Adjuvant Activity of BCG Cell Wall Cytoskeleton on a Dengue Virus-2 Subunit Vaccine.

Tuksin Jearanaiwitayakul, Saradee Warit, Kritsadayut Lekjinda, Mathurin Seesen, Jitra Limthongkul, Panuwat Midoeng, Panya Sunintaboon, Sukathida Ubol

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tuksin JearanaiwitayakulDepartment of Clinical Pathology, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok 10300, Thailand.ORCID 0000-0002-2555-8516
Saradee WaritTuberculosis Research Laboratory, Medical Molecular Biology Research Unit, BIOTEC, National Science and Technology Development Agency, Thailand Science Park, Pathum Thani 12120, Thailand.
Kritsadayut LekjindaDepartment of Chemistry, Faculty of Science, Mahidol University, Salaya 73170, Thailand.
Mathurin SeesenDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Jitra LimthongkulDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Panuwat MidoengDivision of Pathology, Army Institute of Pathology, Phramongkutklao Hospital, Bangkok 10400, Thailand.
Panya SunintaboonDepartment of Chemistry, Faculty of Science, Mahidol University, Salaya 73170, Thailand.
Sukathida UbolDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Mahidol University · THNational Science and Technology Development Agency · THPhramongkutklao Hospital · TH

Funding

National Vaccine Institute, Thailand 2558.1/7
6 · The paper itself

Abstract

The uneven immunogenicity of the attenuated tetravalent dengue vaccine has made it difficult to achieve balanced protection against all four serotypes of the dengue virus (DENV). To overcome this problem, non-replicative vaccines have come into focus, as their immunogenicity is adjustable. This approach is excellent for multivalent vaccines but commonly faces the issue of low immunogenicity. In this present study, we developed a non-replicating dengue vaccine composed of UV-inactivated dengue virus-2 (UV-DENV-2) and DENV-2 NS

Indexed as

BCG cell wall cytoskeletondengue nanovaccinenon-structural protein 1UV-inactivated dengue virus-2

Identifiers

PMID37631912
PMCPMC10459381
OpenAlexW4385690278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.