Evidence map›Paper›PMID 37631857›Full record

ReviewVaccines2023

A Systematic Review of Population-Based Studies Assessing Knowledge, Attitudes, Acceptance, and Hesitancy of Pregnant and Breastfeeding Women towards the COVID-19 Vaccine.

Vincenza Gianfredi, Pasquale Stefanizzi, Alessandro Berti, Marilena D'Amico, Viola De Lorenzo, Antonio Di Lorenzo, Lorenza Moscara, Silvana Castaldi

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Acceptance of the COVID-19 Vaccine Among Postpartum Women in Five Countries.Women's health reports (New Rochelle, N.Y.) · 2025
    Article
  11. Knowledge and attitudes of pregnant women about COVID-19 vaccination.Revista latino-americana de enfermagem · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Vaccination Open Day: A Cross-Sectional Study on the 2023 Experience in Lombardy Region, Italy.International journal of environmental research and public health · 2024
    Article
  17. Review
  18. Knowledge, attitude, and acceptance of COVID-19 vaccine in pregnant women.Therapeutic advances in vaccines and immunotherapy · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vincenza GianfrediDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal, 36, 20133 Milan, Italy.ORCID 0000-0003-3848-981X
Pasquale StefanizziInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70121 Bari, Italy.ORCID 0000-0002-3279-0196
Alessandro BertiDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal, 36, 20133 Milan, Italy.ORCID 0009-0007-5409-9041
Marilena D'AmicoDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal, 36, 20133 Milan, Italy.
Viola De LorenzoDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal, 36, 20133 Milan, Italy.ORCID 0000-0002-2376-0972
Antonio Di LorenzoInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70121 Bari, Italy.
Lorenza MoscaraInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Piazza G. Cesare 11, 70121 Bari, Italy.
Silvana CastaldiDepartment of Biomedical Sciences for Health, University of Milan, Via Pascal, 36, 20133 Milan, Italy.ORCID 0000-0003-1716-6624
University of Milan · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-SARS-CoV-2 vaccination is recommended for pregnant women due to the high risk of complications. However, pregnancy has been associated with vaccine hesitancy. Our review aims at summarizing the existing literature about anti-SARS-CoV-2 vaccine hesitancy in pregnant and lactating women. The research was conducted on PubMed/MEDLINE, ExcerptaMedica Database (EMBASE), and Scopus, according to PRISMA guidelines. Articles regarding the COVID-19 vaccine's acceptance and/or refusal by pregnant and lactating women were selected. Only observational, population-based studies were included. The Joanna Briggs Institute quality assessment tools were employed. A total of 496 articles were retrieved, and after the selection process, 21 papers were included in the current analysis. All the included studies were cross-sectional, mostly from Europe and North America. The sample sizes ranged between 72 and 25,111 subjects. All of them included pregnant subjects, except one that focused on breastfeeding women only. Vaccine hesitancy rates ranged from 26% to 57% among different studies. Fear of adverse events and lack of knowledge were shown to be the main drivers of hesitancy. Approximately half of the studies (11/21) were classified as low quality, the remaining (9/21) were classified as moderate, and only one study was classified as high quality. Primigravidae were also shown to be more likely to accept anti-SARS-CoV-2 vaccination. Our findings confirm significant anti-SARS-CoV-2 vaccine hesitancy among pregnant women. Information gaps should be addressed to contain concerns related to adverse events.

Indexed as

acceptanceattitudebreastfeedingCOVID-19 vaccinehesitancyknowledgelactatingpregnant women

Identifiers

PMID37631857
PMCPMC10459271
OpenAlexW4385349114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.