Evidence map›Paper›PMID 37631391›Full record

ArticlePolymers2023

Gelatin-Functionalized Carbon Nanotubes Loaded with Cisplatin for Anti-Cancer Therapy.

Rong Li, Zhenfei Bao, Pei Wang, Yunyun Deng, Junping Fan, Xin Zhu, Xinyu Xia, Yiming Song, Haiyan Yao, Dongfang Li

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rong LiSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Zhenfei BaoSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Pei WangSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Yunyun DengSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Junping FanSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Xin ZhuSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Xinyu XiaSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Yiming SongSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Haiyan YaoSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Dongfang LiSchool of Stomatology, Nanchang University, Nanchang 330006, China.
Nanchang University · CN

Funding

National Natural Science Foundation of China 82260199The Jiangxi Provincial Natural Science Foundation 20161BAB205231
6 · The paper itself

Abstract

Cisplatin (Cp), a chemotherapeutic agent, interacts with purines on tumor DNA, causing tumor cell apoptosis. However, cisplatin has the characteristics of non-specific distribution and lack of selectivity, resulting in systemic toxicity. Moreover, it cannot maintain the drug's high concentration in the tumor-weak acid environment. These flaws of cisplatin restrict its use in clinical applications. Therefore, a pH-responsive carbon nanotube-modified nano-drug delivery system (CNTs/Gel/Cp) was constructed in this study using gelatin (Gel)-modified carbon nanotubes (CNTs/Gel) loaded with cisplatin to release drugs precisely and slowly, preventing premature inactivation and maintaining an effective concentration. When M

Indexed as

biocompatibilitycarbon nanotubescisplatindrug delivery systemsrelease

Identifiers

PMID37631391
PMCPMC10458187
OpenAlexW4385655114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.