Evidence map›Paper›PMID 37631342›Full record

ArticlePharmaceutics2023

Cinnamyl-Modified Polyglycidol/Poly(ε-Caprolactone) Block Copolymer Nanocarriers for Enhanced Encapsulation and Prolonged Release of Cannabidiol.

Natalia Toncheva-Moncheva, Erik Dimitrov, Georgi Grancharov, Denitsa Momekova, Petar Petrov, Stanislav Rangelov

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Natalia Toncheva-MonchevaInstitute of Polymers, Bulgarian Academy of Sciences, "Akad. G. Bonchev" Street., bl. 103A, 1113 Sofia, Bulgaria.ORCID 0000-0002-7257-1107
Erik DimitrovInstitute of Polymers, Bulgarian Academy of Sciences, "Akad. G. Bonchev" Street., bl. 103A, 1113 Sofia, Bulgaria.
Georgi GrancharovInstitute of Polymers, Bulgarian Academy of Sciences, "Akad. G. Bonchev" Street., bl. 103A, 1113 Sofia, Bulgaria.
Denitsa MomekovaDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav Street, 1000 Sofia, Bulgaria.ORCID 0000-0001-8112-6761
Petar PetrovInstitute of Polymers, Bulgarian Academy of Sciences, "Akad. G. Bonchev" Street., bl. 103A, 1113 Sofia, Bulgaria.ORCID 0000-0002-5777-2066
Stanislav RangelovInstitute of Polymers, Bulgarian Academy of Sciences, "Akad. G. Bonchev" Street., bl. 103A, 1113 Sofia, Bulgaria.
Bulgarian Academy of Sciences · BGMedical University of Sofia · BG

Funding

National Research Programme "Innovative Low-Toxic Bioactive Systems for Precision Medicine (BioActive-Med)" D01-217/30.11.2018
6 · The paper itself

Abstract

The present study describes the development of novel block copolymer nanocarriers of the phytocannabinoid cannabidiol (CBD), designed to enhance the solubility of the drug in water while achieving high encapsulation efficiency and prolonged drug release. Firstly, a well-defined amphiphilic block copolymer consisting of two outer hydrophilic polyglycidol (PG) blocks and a middle hydrophobic block of poly(ε-caprolactone) bearing pendant cinnamyl moieties (P(CyCL-

Indexed as

cannabidiolclick reactionsfunctional nanomaterialspolyglycidolpoly(ε-caprolactone)self-assembly

Identifiers

PMID37631342
PMCPMC10459144
OpenAlexW4385795862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.