Evidence map›Paper›PMID 37631338›Full record

ArticlePharmaceutics2023

Cytotoxicity Analysis and In Silico Studies of Three Plant Extracts with Potential Application in Treatment of Endothelial Dysfunction.

Andreea Roxana Ungureanu, Violeta Popovici, Camelia Oprean, Corina Danciu, Verginica Schröder, Octavian Tudorel Olaru, Dragoș Paul Mihai, Liliana Popescu, Emanuela-Alice Luță, Carmen Lidia Chițescu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Preliminary Investigation ofAntioxidants (Basel, Switzerland) · 2024
    Article
  4. Antioxidant and Cytotoxic Properties ofMolecules (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Andreea Roxana UngureanuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0009-0001-1228-9425
Violeta PopoviciDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.ORCID 0000-0001-9696-5728
Camelia OpreanFaculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2 Eftimie Murgu Street, 300041 Timisoara, Romania.
Corina DanciuFaculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2 Eftimie Murgu Street, 300041 Timisoara, Romania.ORCID 0000-0001-5999-1214
Verginica SchröderDepartment of Cellular and Molecular Biology, Faculty of Pharmacy, Ovidius University of Constanta, 6 Capitan Al. Serbanescu Street, 900001 Constanta, Romania.ORCID 0000-0001-8876-1901
Octavian Tudorel OlaruFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0001-6904-3066
Dragoș Paul MihaiFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0003-2880-9381
Liliana PopescuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Emanuela-Alice LuțăFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0002-6903-3260
Carmen Lidia ChițescuFaculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galați, A.I. Cuza 35, 800010 Galați, Romania.ORCID 0000-0002-3212-7431
Cerasela Elena GîrdFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.ORCID 0000-0003-4372-4335
Carol Davila University of Medicine and Pharmacy · ROOvidius University · RO"Dunarea de Jos" University of Galati · ROSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial dysfunction is the basis of the physiopathological mechanisms of vascular diseases. In addition to the therapeutic activity of plant extracts, cytotoxicity is significant. This research evaluates the cytotoxicity of three vegetal extracts (

Indexed as

brine shrimp lethality assayCalendulae flos extractcaspasescytotoxicityendothelial cellsGinkgo bilobae folium extractmolecular dockingSophorae flos extract

Identifiers

PMID37631338
PMCPMC10459174
OpenAlexW4385760601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.