Evidence map›Paper›PMID 37631280›Full record

ReviewPharmaceutics2023

Plasma Modification Techniques for Natural Polymer-Based Drug Delivery Systems.

Pankaj Bhatt, Vipin Kumar, Vetriselvan Subramaniyan, Kandasamy Nagarajan, Mahendran Sekar, Suresh V Chinni, Gobinath Ramachawolran

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pankaj BhattKIET School of Pharmacy, KIET Group of Institutions, Ghaziabad 201206, Uttar Pradesh, India.ORCID 0000-0003-1341-7422
Vipin KumarDepartment of Pharmaceutical Sciences, Gurukul Kangri (Deemed to Be University), Haridwar 249404, Uttarakhand, India.ORCID 0000-0002-7557-6720
Vetriselvan SubramaniyanJeffrey Cheah School of Medicine and Health Sciences, Monash University, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.ORCID 0000-0002-9629-9494
Kandasamy NagarajanKIET School of Pharmacy, KIET Group of Institutions, Ghaziabad 201206, Uttar Pradesh, India.
Mahendran SekarSchool of Pharmacy, Monash University Malaysia, Subang Jaya 47500, Selangor, Malaysia.ORCID 0000-0002-3022-6137
Suresh V ChinniDepartment of Biochemistry, Faculty of Medicine, Bioscience, and Nursing, MAHSA University, Jenjarom 42610, Selangor, Malaysia.ORCID 0000-0002-4697-2994
Gobinath RamachawolranDepartment of Foundation, RCSI & UCD Malaysia Campus, No. 4, Jalan Sepoy Lines, Georgetown 10450, Pulau Pinang, Malaysia.ORCID 0000-0001-5482-031X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural polymers have attracted significant attention in drug delivery applications due to their biocompatibility, biodegradability, and versatility. However, their surface properties often limit their use as drug delivery vehicles, as they may exhibit poor wettability, weak adhesion, and inadequate drug loading and release. Plasma treatment is a promising surface modification technique that can overcome these limitations by introducing various functional groups onto the natural polymer surface, thus enhancing its physicochemical and biological properties. This review provides a critical overview of recent advances in the plasma modification of natural polymer-based drug delivery systems, with a focus on controllable plasma treatment techniques. The review covers the fundamental principles of plasma generation, process control, and characterization of plasma-treated natural polymer surfaces. It discusses the various applications of plasma-modified natural polymer-based drug delivery systems, including improved biocompatibility, controlled drug release, and targeted drug delivery. The challenges and emerging trends in the field of plasma modification of natural polymer-based drug delivery systems are also highlighted. The review concludes with a discussion of the potential of controllable plasma treatment as a versatile and effective tool for the surface functionalization of natural polymer-based drug delivery systems.

Indexed as

biocompatibilitydrug deliveryplasma diagnosticsplasma modificationplasma parameterssurface functionalizationsurface modification

Identifiers

PMID37631280
PMCPMC10459779

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.