Evidence map›Paper›PMID 37631279›Full record

ReviewPharmaceutics2023

Overview of Solid Lipid Nanoparticles in Breast Cancer Therapy.

Kyumin Mo, Ayoung Kim, Soohyun Choe, Miyoung Shin, Hyunho Yoon

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Tailoring biomaterials for vaccine delivery.Journal of nanobiotechnology · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyumin MoDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Ayoung KimDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Soohyun ChoeDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
Miyoung ShinDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0001-9825-1016
Hyunho YoonDepartment of Medical and Biological Sciences, The Catholic University of Korea, Bucheon 14662, Republic of Korea.ORCID 0000-0003-1853-9701

Funding

Brain Korea 21 M2022B002600003
6 · The paper itself

Abstract

Lipid nanoparticles (LNPs), composed of ionized lipids, helper lipids, and cholesterol, provide general therapeutic effects by facilitating intracellular transport and avoiding endosomal compartments. LNP-based drug delivery has great potential for the development of novel gene therapies and effective vaccines. Solid lipid nanoparticles (SLNs) are derived from physiologically acceptable lipid components and remain robust at body temperature, thereby providing high structural stability and biocompatibility. By enhancing drug delivery through blood vessels, SLNs have been used to improve the efficacy of cancer treatments. Breast cancer, the most common malignancy in women, has a declining mortality rate but remains incurable. Recently, as an anticancer drug delivery system, SLNs have been widely used in breast cancer, improving the therapeutic efficacy of drugs. In this review, we discuss the latest advances of SLNs for breast cancer treatment and their potential in clinical use.

Indexed as

breast cancercancer therapydrug deliverysolid lipid nanoparticle

Identifiers

PMID37631279
PMCPMC10457810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.